3E07

Crystal structure of spatzle cystine knot

Summary for 3E07

Entry DOI	10.2210/pdb3e07/pdb
Descriptor	Protein spaetzle, GLYCEROL (3 entities in total)
Functional Keywords	cystine knot, toll ligand, antimicrobial, cytokine, developmental protein, fungicide, glycoprotein, secreted
Biological source	Drosophila melanogaster (Fruit fly)
Cellular location	Isoform 8. Isoform 8. Isoform 11. Isoform 11. Isoform 11: P48607
Total number of polymer chains	2
Total formula weight	26105.33
Authors	Hoffmann, A.,Funkner, A.,Neumann, P.,Juhnke, S.,Walther, M.,Schierhorn, A.,Weininger, U.,Balbach, J.,Reuter, G.,Stubbs, M.T. (deposition date: 2008-07-31, release date: 2008-09-23, Last modification date: 2023-11-01)
Primary citation	Hoffmann, A.,Funkner, A.,Neumann, P.,Juhnke, S.,Walther, M.,Schierhorn, A.,Weininger, U.,Balbach, J.,Reuter, G.,Stubbs, M.T. Biophysical Characterization of Refolded Drosophila Spatzle, a Cystine Knot Protein, Reveals Distinct Properties of Three Isoforms J.Biol.Chem., 283:32598-32609, 2008 Cited by PubMed: 18790733 DOI: 10.1074/jbc.M801815200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation