4LXR
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein toll | polymer | 783 | 89632.4 | 1 | UniProt (P08953) Pfam (PF13855) Pfam (PF00560) Pfam (PF01463) Pfam (PF01462) In PDB | Drosophila melanogaster (Fruit fly) | |
| 2 | J, K | Protein spaetzle C-106 | polymer | 114 | 13006.6 | 2 | UniProt (P48607) Pfam (PF16077) In PDB | Drosophila melanogaster (Fruit fly) | |
| 3 | B | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G52322TF) | |||
| 4 | C, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 7 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 8 | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A: 28 - 802 (UniProt: P08953)
J, K: 1 - 106 (UniProt: P48607)
| PDB | External Database | Details |
|---|---|---|
| Thr 803 | - | expression tag |
| Gly 804 | - | expression tag |
| His 805 | - | expression tag |
| His 806 | - | expression tag |
| His 807 | - | expression tag |
| His 808 | - | expression tag |
| His 809 | - | expression tag |
| His 810 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 107 | - | expression tag |
| Glu 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| His 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 115645.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2346.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1565.6 | |
| All* | Total formula weight | 119557.4 |
