PDB: 160 件ウェブページステータス検索Chemie searchBIRD

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3FWT	Crystal structure of Leishmania major MIF2 分子名称: Macrophage migration inhibitory factor-like protein 著者 Walkinshaw, M.D, Richardson, J.M. 登録日 2009-01-19 公開日 2009-03-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of Leishmania major orthologues of macrophage migration inhibitory factor Biochem.Biophys.Res.Commun., 380, 2009
3GAD	Structure of apomif 分子名称: ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION 著者 Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. 登録日 2009-02-17 公開日 2009-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
3GAC	Structure of mif with HPP 分子名称: 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ACETIC ACID, Macrophage migration inhibitory factor-like protein, ... 著者 Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. 登録日 2009-02-17 公開日 2009-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
3HOF	Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution 分子名称: CAFFEIC ACID, Macrophage migration inhibitory factor 著者 Crawley, L, Barker, J, Cheng, R.K.Y, Wood, M, Felicetti, B. 登録日 2009-06-02 公開日 2009-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution To be Published
2WKF	Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum 分子名称: GLYCEROL, MACROPHAGE MIGRATION INHIBITORY FACTOR 著者 Dobson, S.E, Augustijn, K.D, Brannigan, J.A, Dodson, E.J, Waters, A.P, Wilkinson, A.J. 登録日 2009-06-11 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei. Protein Sci., 18, 2009
3IJJ	Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer) 分子名称: (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ... 著者 Crichlow, G.V, Cho, Y, Lolis, E.J. 登録日 2009-08-04 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
3IJG	Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013 分子名称: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor 著者 Crichlow, G.V, Cho, Y, Lolis, E.J. 登録日 2009-08-04 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
3JSF	Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 638 at 1.93a resolution 分子名称: 7-(2-fluorobenzyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION 著者 Mclean, L, Zhang, Y. 登録日 2009-09-10 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening. Bioorg.Med.Chem.Lett., 19, 2009
3JSG	Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 707 at 1.58a resolution 分子名称: 7-(pyridin-3-ylmethyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION 著者 Mclean, L, Zhang, Y. 登録日 2009-09-10 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening. Bioorg.Med.Chem.Lett., 19, 2009
3JTU	Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 708 at 1.86a resolution 分子名称: 7-(pyridin-2-ylmethyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION 著者 Mclean, L, Zhang, Y. 登録日 2009-09-14 公開日 2009-11-10 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening. Bioorg.Med.Chem.Lett., 19, 2009
3KAN	D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP 分子名称: 4-phenylpyrimidine, CHLORIDE ION, D-dopachrome tautomerase 著者 Zierow, S, Lolis, E. 登録日 2009-10-19 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment. Faseb J., 28, 2014
3KER	D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP 分子名称: 4-phenylpyrimidine, CHLORIDE ION, D-dopachrome decarboxylase, ... 著者 Zierow, S, Lolis, E. 登録日 2009-10-26 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment. Faseb J., 28, 2014
3L5R	Crystal structure of macrophage migration inhibitory factor (MIF) with phenylchromenone inhibitor at 1.94A resolution 分子名称: 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
3L5U	Crystal structure of macrophage migration inhibitory factor (MIF) with benzothiazole inhibitor at 1.90A resolution 分子名称: 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE, Macrophage migration inhibitory factor, SULFATE ION 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
3L5S	Crystal structure of macrophage migration inhibitory factor (MIF) with imidazopyrimidinylphenyl inhibitor at 1.86A resolution 分子名称: 5-ethyl-2-(phenylcarbonyl)imidazo[1,2-a]pyrimidin-7(1H)-one, Macrophage migration inhibitory factor, SULFATE ION 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
3L5V	Crystal structure of macrophage migration inhibitory factor (MIF) with glycerol at 1.70A resolution 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
3L5P	Crystal structure of macrophage migration inhibitory factor (MIF) with imidazopyridazinol inhibitor at 1.80A resolution 分子名称: 2-(1-methylethyl)imidazo[1,2-b]pyridazin-6-ol, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
3L5T	Crystal structure of macrophage migration inhibitory factor (MIF) with thiophenepiperazinylquinolinone inhibitor at 1.86A resolution 分子名称: 1-methyl-2-oxo-4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]-1,2-dihydroquinoline-3-carbonitrile, Macrophage migration inhibitory factor, SULFATE ION 著者 McLean, L, Zhang, Y. 登録日 2009-12-22 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20, 2010
2XCZ	Crystal Structure of macrophage migration inhibitory factor homologue from Prochlorococcus marinus 分子名称: DI(HYDROXYETHYL)ETHER, POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN 著者 Wasiel, A.A, Rozeboom, H.J, Hauke, D, Baas, B.J, Zandvoort, E, Quax, W.J, Thunnissen, A.M.W.H, Poelarends, G.J. 登録日 2010-04-27 公開日 2010-09-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus Marinus. Biochemistry, 49, 2010
3RF4	Ancylostoma ceylanicum mif in complex with furosemide 分子名称: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, ACETATE ION, IMIDAZOLE, ... 著者 Cho, Y, Lolis, E. 登録日 2011-04-05 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18, 2011
3RF5	Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide 分子名称: 2-[(furan-2-ylmethyl)amino]benzoic acid, ACETATE ION, IMIDAZOLE, ... 著者 Cho, Y, Lolis, E. 登録日 2011-04-05 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18, 2011
3SMC	Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound L-sulforaphane 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N-{4-[(R)-methylsulfinyl]butyl}thioformamide, ... 著者 Crichlow, G.V, Lolis, E.J. 登録日 2011-06-27 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates. Biochemistry, 51, 2012
3SMB	Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF) 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ... 著者 Crichlow, G.V, Lolis, E.J. 登録日 2011-06-27 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates. Biochemistry, 51, 2012
3T5S	Structure of macrophage migration inhibitory factor from Giardia lamblia 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-07-28 公開日 2011-08-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. J.Struct.Funct.Genom., 14, 2013
3U18	Chicago Sky Blue 6B, A Novel Inhibitor for Macrophage Migration Inhibitory Factor 分子名称: 1,2-ETHANEDIOL, 6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid), GLYCEROL, ... 著者 Asojo, O.A. 登録日 2011-09-29 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF). J.Biol.Chem., 287, 2012

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