3L5V

Crystal structure of macrophage migration inhibitory factor (MIF) with glycerol at 1.70A resolution

Summary for 3L5V

Entry DOI	10.2210/pdb3l5v/pdb
Related	3L5P 3L5R 3L5S 3L5T 3L5U
Descriptor	Macrophage migration inhibitory factor, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywords	protein-ligand complex, cytokine, cytoplasm, immune response, inflammatory response, innate immunity, isomerase, phosphoprotein, secreted, acetylation
Biological source	Homo sapiens (human)
Cellular location	Secreted : P14174
Total number of polymer chains	3
Total formula weight	40843.10
Authors	McLean, L.,Zhang, Y. (deposition date: 2009-12-22, release date: 2010-03-09, Last modification date: 2023-09-06)
Primary citation	McLean, L.R.,Zhang, Y.,Li, H.,Choi, Y.M.,Han, Z.,Vaz, R.J.,Li, Y. Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg.Med.Chem.Lett., 20:1821-1824, 2010 Cited by PubMed: 20185308 DOI: 10.1016/j.bmcl.2010.02.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation