3L5V
Crystal structure of macrophage migration inhibitory factor (MIF) with glycerol at 1.70A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Macrophage migration inhibitory factor | polymer | 122 | 13426.2 | 3 | UniProt (P14174) Pfam (PF01187) In PDB | Homo sapiens (human) | MIF, Phenylpyruvate tautomerase, L-dopachrome tautomerase, L-dopachrome isomerase, Glycosylation-inhibiting factor, GIF |
2 | A, B, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
3 | A, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 114 (UniProt: P14174)
PDB | External Database | Details |
---|---|---|
Leu 115 | - | expression tag |
Glu 116 | - | expression tag |
His 117 | - | expression tag |
His 118 | - | expression tag |
His 119 | - | expression tag |
His 120 | - | expression tag |
His 121 | - | expression tag |
His 122 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 40278.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 564.5 | |
All* | Total formula weight | 40843.1 |