PDB: 166 件ウェブページステータス検索Chemie searchBIRD

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5Y5P	Crystal structure of the dUTPase of white spot syndrome virus in complex with dU,PPi and Mg2+ 分子名称: 2'-DEOXYURIDINE, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
6MJK	Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri in complex with deoxyuridine 分子名称: 2'-DEOXYURIDINE, MAGNESIUM ION, PYROPHOSPHATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-09-21 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri in complex with deoxyuridine to be published
5Y5Q	Crystal structure of the WSSV dUTPase D88N/R158E mutant in complex with dUTP 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Wsv112 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
1XS4	dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION 著者 Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. 登録日 2004-10-18 公開日 2004-12-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
4GK6	X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus 分子名称: CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-08-10 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
5Y5O	Crystal structure of the dUTPase of white spot syndrome virus in the apo state 分子名称: Wsv112 著者 Ma, Q, Zang, K. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner. J. Biol. Chem., 293, 2018
4GV8	DUTPase from phage phi11 of S.aureus: visualization of the species-specific insert 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Leveles, I, Harmat, V, Nemeth, V, Bendes, A, Szabo, J, Kadar, V, Zagyva, I, Rona, G, Toth, J, Vertessy, B.G. 登録日 2012-08-30 公開日 2013-09-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and enzymatic mechanism of a moonlighting dUTPase Acta Crystallogr.,Sect.D, 69, 2013
1XS1	dCTP deaminase from Escherichia coli in complex with dUTP 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION 著者 Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. 登録日 2004-10-18 公開日 2004-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
1XS6	dCTP deaminase from Escherichia coli. E138A mutant enzyme in complex with dUTP 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION 著者 Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. 登録日 2004-10-18 公開日 2004-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
6MAO	Crystal structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase from Legionella pneumophila Philadelphia 1 in complex with dUMP (Deoxyuridine 5'-monophosphate) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-08-28 公開日 2018-09-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase from Legionella pneumophila Philadelphia 1 in complex with dUMP (Deoxyuridine 5'-monophosphate) TO BE PUBLISHED
5CCT	Staphylococcus bacteriophage 80alpha dUTPase G164S mutant with dUpNHpp. 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Maiques, E, Quiles-Puchalt, N, Donderis, J, Ciges, J.R, Alite, C, Bowring, J, Penades, J.R, Marina, A. 登録日 2015-07-02 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Another look at the mechanism involving trimeric dUTPases in Staphylococcus aureus pathogenicity island induction involves novel players in the party. Nucleic Acids Res., 44, 2016
3EHW	Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, dUTP pyrophosphatase 著者 Takacs, E, Barabas, O, Vertessy, B.G. 登録日 2008-09-15 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site To be Published
5CCO	Staphylococcus bacteriophage 80alpha dUTPase with dUMP. 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DUTPase, MAGNESIUM ION 著者 Maiques, E, Quiles-Puchalt, N, Donderis, J, Ciges, J.R, Alite, C, Bowring, J, Penades, J.R, Marina, A. 登録日 2015-07-02 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Another look at the mechanism involving trimeric dUTPases in Staphylococcus aureus pathogenicity island induction involves novel players in the party. Nucleic Acids Res., 44, 2016
5ECT	Mycobacterium tuberculosis dUTPase G143STOP mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Nagy, G.N, Leveles, I, Harmat, V, Vertessy, G.B. 登録日 2015-10-20 公開日 2016-11-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases. J. Am. Chem. Soc., 138, 2016
5EDD	Crystal structure of Mycobacterium tuberculosis dUTPase R140K, H145W mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Nagy, G.N, Leveles, I, Lopata, A, Harmat, V, Toth, J, Vertessy, G.B. 登録日 2015-10-21 公開日 2016-11-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases. J. Am. Chem. Soc., 138, 2016
3F4F	Crystal structure of dUT1p, a dUTPase from Saccharomyces cerevisiae 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Singer, A.U, Evdokimova, E, Kudritska, M, Edwards, A.M, Yakunin, A.F, Savchenko, A. 登録日 2008-10-31 公開日 2008-11-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437, 2011
3GF0	Bifunctional dCTP deaminase-dUTPase mutant enzyme variant E145Q from Methanocaldococcus jannaschii in complex with pyrophosphate and magnesium 分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, dCTP deaminase, ... 著者 Siggaard, J.H.B, Johansson, E, Vognsen, T, Helt, S.S, Harris, P, Willemoes, M. 登録日 2009-02-26 公開日 2009-03-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Pre-steady State Kinetic and Structural Evidence for a Concerted Biofunctionality in dCTP deaminase-dUTPase from Methanocaldococcus jannaschii To be Published
3ECY	Crystal structural analysis of Drosophila melanogaster dUTPase 分子名称: CG4584-PA, isoform A (BcDNA.LD08534) 著者 Takacs, E, Barabas, O, Vertessy, B.G. 登録日 2008-09-02 公開日 2008-10-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers. Febs Lett., 583, 2009
3H6X	Crystal structure of dUTPase from Streptococcus mutans 分子名称: dUTPase 著者 Li, G.L, Wang, K.T, Liu, X, Li, L.F, Su, X.D. 登録日 2009-04-24 公開日 2010-05-05 最終更新日 2018-05-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and activity analysis of dUTP nucleotidohydrolase from Streptococcus mutans To be Published
3LQW	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica 分子名称: 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-02-10 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica To be Published
3LOJ	Structure of Mycobacterium tuberculosis dUTPase H145A mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Leveles, I, Harmat, V, Pecsi, I, Lopata, A, Vertessy, B.G, Toth, J. 登録日 2010-02-04 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase Nucleic Acids Res., 38, 2010
3HHQ	Crystal structure of apo dUT1p from Saccharomyces cerevisiae 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Singer, A.U, Evdokimova, E, Kudritska, M, Dong, A, Edwards, A.M, Yakunin, A.F, Savchenko, A. 登録日 2009-05-15 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437, 2011
3I93	Crystal structure of Mycobacterium tuberculosis dUTPase STOP138T mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Leveles, I, Harmat, V, Lopata, A, Toth, J, Vertessy, B.G. 登録日 2009-07-10 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584, 2010
3MDX	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form 分子名称: 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-31 公開日 2010-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form To be Published
3HZA	Crystal structure of dUTPase H145W mutant 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... 著者 Leveles, I, Harmat, V, Pecsi, I, Toth, J, Vertessy, B.G. 登録日 2009-06-23 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res., 38, 2010

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