3P48

Structure of the yeast dUTPase DUT1 in complex with dUMPNPP

Summary for 3P48

Entry DOI	10.2210/pdb3p48/pdb
Related	3F4F 3HHQ
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	trimer, beta barrel, dumppnp pyrophosphatase, hydrolase, phosphoprotein, structural genomics, ontario centre for structural proteomics, ocsp
Biological source	Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
Total number of polymer chains	3
Total formula weight	47444.18
Authors	Petit, P.,Singer, A.U.,Evdokimova, E.,Kudritska, M.,Edwards, A.M.,Yakunin, A.F.,Savchenko, A.,Ontario Centre for Structural Proteomics (OCSP) (deposition date: 2010-10-06, release date: 2010-10-27, Last modification date: 2023-09-06)
Primary citation	Tchigvintsev, A.,Singer, A.U.,Flick, R.,Petit, P.,Brown, G.,Evdokimova, E.,Savchenko, A.,Yakunin, A.F. Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437:243-253, 2011 Cited by PubMed: 21548881 DOI: 10.1042/BJ20110304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation