Mycobacterium tuberculosis dUTPase G143STOP mutant

Summary for 5ECT

Related4GCY 3LOJ 3I93 3HZA 3H6D 2PY4 1SJN 1SIX 1MQ7 1SNF 1SLH 1SMC
DescriptorDeoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
Functional Keywordshydrolase, jelly-roll, trimer
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight17690.99
Nagy, G.N.,Leveles, I.,Harmat, V.,Vertessy, G.B. (deposition date: 2015-10-20, release date: 2016-11-02, Last modification date: 2016-12-21)
Primary citation
Nagy, G.N.,Suardiaz, R.,Lopata, A.,Ozohanics, O.,Vekey, K.,Brooks, B.R.,Leveles, I.,Toth, J.,Vertessy, B.G.,Rosta, E.
Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
J. Am. Chem. Soc., 138:15035-15045, 2016
PubMed: 27740761 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.6b09012
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1600006.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution