Structure of the mycobacterium tuberculosis DUTPase D28N mutant

Summary for 3H6D

DescriptorDeoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordsjelly-roll, hydrolase, nucleotide metabolism
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight18727.08
Leveles, I.,Harmat, V.,Nagy, G.,Takacs, E.,Lopata, A.,Toth, J.,Vertessy, B.G. (deposition date: 2009-04-23, release date: 2009-11-24, Last modification date: 2011-07-13)
Primary citation
Takacs, E.,Nagy, G.,Leveles, I.,Harmat, V.,Lopata, A.,Toth, J.,Vertessy, B.G.
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584:3047-3054, 2010
PubMed: 20493855 (PDB entries with the same primary citation)
DOI: 10.1016/j.febslet.2010.05.018
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227500.9%8.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-07-29