3LOJ

Structure of Mycobacterium tuberculosis dUTPase H145A mutant

Summary for 3LOJ

Entry DOI	10.2210/pdb3loj/pdb
Related	3HZA
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, GLYCEROL, ... (7 entities in total)
Functional Keywords	hydrolase, jelly roll, domain swapping, nucleotide metabolism, magnesium, metal-binding
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	18777.98
Authors	Leveles, I.,Harmat, V.,Pecsi, I.,Lopata, A.,Vertessy, B.G.,Toth, J. (deposition date: 2010-02-04, release date: 2010-08-11, Last modification date: 2023-11-01)
Primary citation	Pecsi, I.,Leveles, I.,Harmat, V.,Vertessy, B.G.,Toth, J. Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase Nucleic Acids Res., 38:7179-7186, 2010 Cited by PubMed: 20601405 DOI: 10.1093/nar/gkq584 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation