3HZA
Crystal structure of dUTPase H145W mutant
Summary for 3HZA
Entry DOI | 10.2210/pdb3hza/pdb |
Descriptor | Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | jelly roll, domain swapping, hydrolase, nucleotide metabolism |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 18838.17 |
Authors | Leveles, I.,Harmat, V.,Pecsi, I.,Toth, J.,Vertessy, B.G. (deposition date: 2009-06-23, release date: 2009-11-24, Last modification date: 2023-09-06) |
Primary citation | Pecsi, I.,Leveles, I.,Harmat, V.,Vertessy, B.G.,Toth, J. Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res., 38:7179-7186, 2010 Cited by PubMed: 20601405DOI: 10.1093/nar/gkq584 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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