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7F9W
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CD25 in complex with Fab
分子名称: Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab
著者Liu, C.
登録日2021-07-05
公開日2022-01-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity.
Sci Rep, 11, 2021
2KMS
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BU of 2kms by Molmil
Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers
分子名称: Complement factor H
著者Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N.
登録日2009-08-04
公開日2009-11-03
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module
J.Mol.Biol., 395, 2010
3ZD2
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BU of 3zd2 by Molmil
THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1
著者Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
登録日2012-11-23
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZD1
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STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2
著者Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
登録日2012-11-23
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
2MCZ
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BU of 2mcz by Molmil
CR1 Sushi domains 1 and 2
分子名称: Complement receptor type 1
著者Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCY
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BU of 2mcy by Molmil
CR1 Sushi domains 2 and 3
分子名称: Complement receptor type 1
著者Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2014-01-22
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2A55
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BU of 2a55 by Molmil
Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.
分子名称: C4b-binding protein
著者Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N.
登録日2005-06-30
公開日2005-12-13
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
2BZM
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BU of 2bzm by Molmil
Solution structure of the primary host recognition region of complement factor H
分子名称: COMPLEMENT FACTOR H
著者Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N.
登録日2005-08-18
公開日2006-03-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281, 2006
2EHF
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BU of 2ehf by Molmil
Solution structure of the third Sushi domain from human CUB and sushi domain-containing protein 1
分子名称: CUB and sushi domain-containing protein 1
著者Inoue, K, Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-06
公開日2007-09-11
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of the third Sushi domain from human CUB and sushi domain-containing protein 1
to be published
2G7I
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BU of 2g7i by Molmil
Structure of Human Complement Factor H Carboxyl Terminal Domains 19-20: a Basis for Atypical Hemolytic Uremic Syndrome
分子名称: Complement factor H
著者Jaakola, V.-P, Jokiranta, T.S, Goldman, A.
登録日2006-02-28
公開日2006-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome.
Embo J., 25, 2006
1UOT
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BU of 1uot by Molmil
HUMAN CD55 DOMAINS 3 & 4
分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR
著者Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
登録日2003-09-23
公開日2003-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1VVE
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BU of 1vve by Molmil
C-TERMINAL HALF OF VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN, NMR, 21 STRUCTURES
分子名称: VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
著者Wiles, A, Campbell, I.D, Barlow, P.N.
登録日1997-06-25
公開日1997-12-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR studies of a viral protein that mimics the regulators of complement activation.
J.Mol.Biol., 272, 1997
1VVD
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BU of 1vvd by Molmil
C-TERMINAL HALF OF VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN, NMR, 21 STRUCTURES
分子名称: VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
著者Wiles, A, Campbell, I.D, Barlow, P.N.
登録日1997-06-25
公開日1997-12-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR studies of a viral protein that mimics the regulators of complement activation.
J.Mol.Biol., 272, 1997
1W2R
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BU of 1w2r by Molmil
Solution structure of CR2 SCR 1-2 by X-ray scattering
分子名称: COMPLEMENT RECEPTOR TYPE 2 PRECURSOR,
著者Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J.
登録日2004-07-08
公開日2005-09-29
最終更新日2024-05-08
実験手法SOLUTION SCATTERING
主引用文献Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
1VVC
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BU of 1vvc by Molmil
C-TERMINAL HALF OF VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
著者Wiles, A, Campbell, I.D, Barlow, P.N.
登録日1997-06-25
公開日1997-12-03
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR studies of a viral protein that mimics the regulators of complement activation.
J.Mol.Biol., 272, 1997
3J24
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BU of 3j24 by Molmil
CryoEM reconstruction of complement decay-accelerating factor
分子名称: Complement decay-accelerating factor
著者Yoder, J.D, Hafenstein, S.H.
登録日2012-08-17
公開日2012-09-26
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface.
J.Virol., 86, 2012
3KZJ
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BU of 3kzj by Molmil
Structure of complement Factor H variant R1203A
分子名称: Complement factor H, SULFATE ION
著者Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S.
登録日2009-12-08
公開日2010-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
3KXV
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Structure of complement Factor H variant Q1139A
分子名称: Complement factor H, SULFATE ION
著者Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S.
登録日2009-12-04
公開日2010-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
5HZP
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BU of 5hzp by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein.
分子名称: C4b-binding protein alpha chain, M protein, serotype 49, ...
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-02
公開日2016-07-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYP
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BU of 5hyp by Molmil
Structure of human C4b-binding protein alpha cain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M28 protein
分子名称: C4b-binding protein alpha chain, M28 protein
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.024 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYT
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Structure of human C4b-binidng protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M22 protein
分子名称: C4b-binding protein alpha chain, Precursor to Protein Sir22
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYU
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BU of 5hyu by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M2 protein
分子名称: C4b-binding protein alpha chain, M protein, serotype 2.1
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5I0Q
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BU of 5i0q by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein
分子名称: C4b-binding protein alpha chain, M protein, serotype 2.1
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-04
公開日2016-07-20
最終更新日2016-10-26
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
4B2S
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BU of 4b2s by Molmil
Solution structure of CCP modules 11-12 of complement factor H
分子名称: COMPLEMENT FACTOR H
著者Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N.
登録日2012-07-17
公開日2012-10-17
最終更新日2013-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
4B2R
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Solution structure of CCP modules 10-11 of complement factor H
分子名称: COMPLEMENT FACTOR H
著者Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N.
登録日2012-07-17
公開日2012-10-10
最終更新日2019-09-25
実験手法SOLUTION NMR
主引用文献Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012

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