7F9W
| CD25 in complex with Fab | 分子名称: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | 著者 | Liu, C. | 登録日 | 2021-07-05 | 公開日 | 2022-01-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
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2KMS
| Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | 分子名称: | Complement factor H | 著者 | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | 登録日 | 2009-08-04 | 公開日 | 2009-11-03 | 最終更新日 | 2020-02-26 | 実験手法 | SOLUTION NMR | 主引用文献 | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module J.Mol.Biol., 395, 2010
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3ZD2
| THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE | 分子名称: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1 | 著者 | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | 登録日 | 2012-11-23 | 公開日 | 2013-03-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZD1
| STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2 | 分子名称: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2 | 著者 | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | 登録日 | 2012-11-23 | 公開日 | 2013-03-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110, 2013
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2MCZ
| CR1 Sushi domains 1 and 2 | 分子名称: | Complement receptor type 1 | 著者 | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | 登録日 | 2013-08-27 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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2MCY
| CR1 Sushi domains 2 and 3 | 分子名称: | Complement receptor type 1 | 著者 | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | 登録日 | 2013-08-27 | 公開日 | 2013-11-13 | 最終更新日 | 2014-01-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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2A55
| Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain. | 分子名称: | C4b-binding protein | 著者 | Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N. | 登録日 | 2005-06-30 | 公開日 | 2005-12-13 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor J.Biol.Chem., 281, 2006
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2BZM
| Solution structure of the primary host recognition region of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | 登録日 | 2005-08-18 | 公開日 | 2006-03-22 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure. J.Biol.Chem., 281, 2006
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2EHF
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2G7I
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1UOT
| HUMAN CD55 DOMAINS 3 & 4 | 分子名称: | COMPLEMENT DECAY-ACCELERATING FACTOR | 著者 | Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | 登録日 | 2003-09-23 | 公開日 | 2003-09-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1VVE
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1VVD
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1W2R
| Solution structure of CR2 SCR 1-2 by X-ray scattering | 分子名称: | COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | 著者 | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | 登録日 | 2004-07-08 | 公開日 | 2005-09-29 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION SCATTERING | 主引用文献 | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study. J.Mol.Biol., 346, 2005
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1VVC
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3J24
| CryoEM reconstruction of complement decay-accelerating factor | 分子名称: | Complement decay-accelerating factor | 著者 | Yoder, J.D, Hafenstein, S.H. | 登録日 | 2012-08-17 | 公開日 | 2012-09-26 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface. J.Virol., 86, 2012
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3KZJ
| Structure of complement Factor H variant R1203A | 分子名称: | Complement factor H, SULFATE ION | 著者 | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | 登録日 | 2009-12-08 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010
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3KXV
| Structure of complement Factor H variant Q1139A | 分子名称: | Complement factor H, SULFATE ION | 著者 | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | 登録日 | 2009-12-04 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010
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5HZP
| Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein. | 分子名称: | C4b-binding protein alpha chain, M protein, serotype 49, ... | 著者 | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | 登録日 | 2016-02-02 | 公開日 | 2016-07-20 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1, 2016
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5HYP
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5HYT
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5HYU
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5I0Q
| Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein | 分子名称: | C4b-binding protein alpha chain, M protein, serotype 2.1 | 著者 | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | 登録日 | 2016-02-04 | 公開日 | 2016-07-20 | 最終更新日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1, 2016
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4B2S
| Solution structure of CCP modules 11-12 of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | 登録日 | 2012-07-17 | 公開日 | 2012-10-17 | 最終更新日 | 2013-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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4B2R
| Solution structure of CCP modules 10-11 of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | 登録日 | 2012-07-17 | 公開日 | 2012-10-10 | 最終更新日 | 2019-09-25 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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