2MCY

CR1 Sushi domains 2 and 3

Summary for 2MCY

Related2MCZ
DescriptorComplement receptor type 1 (1 entity in total)
Functional Keywordscr1, pfrh4, malaria, ccp, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P17927
Total number of polymer chains1
Total molecular weight14675.49
Authors
Park, H.J.,Guariento, M.J.,Maciejewski, M.,Hauart, R.,Tham, W.,Cowman, A.F.,Schmidt, C.Q.,Martens, H.,Liszewski, K.M.,Hourcade, D.,Barlow, P.N.,Atkinson, J.P. (deposition date: 2013-08-27, release date: 2013-11-13, Last modification date: 2014-01-22)
Primary citation
Park, H.J.,Guariento, M.,Maciejewski, M.,Hauhart, R.,Tham, W.H.,Cowman, A.F.,Schmidt, C.Q.,Mertens, H.D.,Liszewski, M.K.,Hourcade, D.E.,Barlow, P.N.,Atkinson, J.P.
Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289:450-463, 2014
PubMed: 24214979 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M113.520346
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers184.8%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures