2VPD
 
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | 分子名称: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION | | 著者 | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | 登録日 | 2008-02-27 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VPB
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | 分子名称: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ... | | 著者 | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | 登録日 | 2008-02-27 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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7W6J
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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4UP0
 | | Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide | | 分子名称: | HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | | 著者 | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | | 登録日 | 2014-06-11 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
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4GUU
 | | Crystal structure of LSD2-NPAC with tranylcypromine | | 分子名称: | Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, ZINC ION, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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5TDR
 | | Set3 PHD finger in complex with histone H3K4me2 | | 分子名称: | Histone H3, SET domain-containing protein 3, SODIUM ION, ... | | 著者 | Andrews, F.H, Ali, M, Kutateladze, T.G. | | 登録日 | 2016-09-19 | | 公開日 | 2016-11-02 | | 最終更新日 | 2025-04-02 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
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4GUS
 | | Crystal structure of LSD2-NPAC with H3 in space group P3221 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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2GNQ
 | | Structure of wdr5 | | 分子名称: | CHLORIDE ION, WD-repeat protein 5 | | 著者 | Min, J, Schuetz, A, Allali-Hassani, A, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-04-10 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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4GUR
 | | Crystal structure of LSD2-NPAC with H3 in space group P21 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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4GUT
 | | Crystal structure of LSD2-NPAC | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1B, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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8INL
 | | LSD1 in complex with S2172 | | 分子名称: | 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Niwa, H, Sato, S, Umehara, T. | | 登録日 | 2023-03-10 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma.
Cancer Gene Ther, 31, 2024
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5TAB
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6E2H
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4FWE
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4FWF
 | | Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ... | | 著者 | Zhang, Q, Chen, Z. | | 登録日 | 2012-07-01 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
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4FWJ
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6TUY
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2O9K
 | | WDR5 in Complex with Dimethylated H3K4 Peptide | | 分子名称: | H3 HISTONE, WD repeat protein 5 | | 著者 | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-12-13 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5.
Embo J., 25, 2006
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4UP5
 | | Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment | | 分子名称: | 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | | 著者 | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | | 登録日 | 2014-06-12 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
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6R1U
 | | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 | | 分子名称: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... | | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | | 登録日 | 2019-03-15 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
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6R25
 | | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 | | 分子名称: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... | | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | | 登録日 | 2019-03-15 | | 公開日 | 2019-04-24 | | 最終更新日 | 2025-04-09 | | 実験手法 | ELECTRON MICROSCOPY (4.61 Å) | | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
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8VLH
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4GU1
 | | Crystal structure of LSD2 | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.939 Å) | | 主引用文献 | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
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4HSU
 | | Crystal structure of LSD2-NPAC with H3(1-26)in space group P21 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Histone H3, Lysine-specific histone demethylase 1B, ... | | 著者 | Chen, F, Dong, Z, Fang, J, Xu, Y. | | 登録日 | 2012-10-30 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | | 主引用文献 | Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
Cell Res., 23, 2013
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6LUK
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