4UP5
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Summary for 4UP5
Entry DOI | 10.2210/pdb4up5/pdb |
Related | 4UP0 |
Descriptor | PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ZINC ION, 6-methoxy-1,3-benzothiazol-2-amine, ... (4 entities in total) |
Functional Keywords | transcription, pygo, wnt signalling, histone h3, fragment screening |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : Q86UU0 |
Total number of polymer chains | 1 |
Total formula weight | 10848.72 |
Authors | Miller, T.C.R.,Fiedler, M.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Bienz, M. (deposition date: 2014-06-12, release date: 2014-11-05, Last modification date: 2024-01-10) |
Primary citation | Miller, T.C.R.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Fiedler, M.,Bienz, M. Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9:2864-, 2014 Cited by PubMed: 25323450DOI: 10.1021/CB500585S PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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