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4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Descriptor: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-11
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
4UP5
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BU of 4up5 by Molmil
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Descriptor: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-12
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
2UWQ
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BU of 2uwq by Molmil
Solution structure of ASPP2 N-terminus
Descriptor: APOPTOSIS-STIMULATING OF P53 PROTEIN 2
Authors:Tidow, H, Rutherford, T.J, Andreeva, A, Fersht, A.R.
Deposit date:2007-03-22
Release date:2007-07-10
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.
J. Mol. Biol., 371, 2007
2FEJ
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BU of 2fej by Molmil
Solution structure of human p53 DNA binding domain.
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R.
Deposit date:2005-12-16
Release date:2006-01-31
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of p53 core domain: Structural basis for its instability
Proc.Natl.Acad.Sci.Usa, 103, 2006
3ZPV
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BU of 3zpv by Molmil
Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain
Descriptor: PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION
Authors:Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M.
Deposit date:2013-03-02
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
2VY5
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BU of 2vy5 by Molmil
U11-48K CHHC Zn-finger protein domain
Descriptor: U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
Authors:Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
Deposit date:2008-07-18
Release date:2009-02-17
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.
Structure, 17, 2009
2VY4
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BU of 2vy4 by Molmil
U11-48K CHHC ZN-FINGER DOMAIN
Descriptor: U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
Authors:Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
Deposit date:2008-07-17
Release date:2009-02-17
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.
Structure, 17, 2009
2WQG
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BU of 2wqg by Molmil
SAP domain from Tho1: L31W (fluorophore) mutant
Descriptor: PROTEIN THO1
Authors:Dodson, C.A, Ferguson, N, Rutherford, T.J, Johnson, C.M, Fersht, A.R.
Deposit date:2009-08-21
Release date:2010-02-16
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Engineering a Two-Helix Bundle Protein for Folding Studies.
Protein Eng.Des.Sel., 23, 2010
2WXC
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BU of 2wxc by Molmil
The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family.
Descriptor: DIHYDROLIPOYLTRANSSUCCINASE
Authors:Neuweiler, H, Sharpe, T.D, Rutherford, T.J, Johnson, C.M, Allen, M.D, Ferguson, N, Fersht, A.R.
Deposit date:2009-11-06
Release date:2009-11-17
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:The Folding Mechanism of Bbl: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family.
J.Mol.Biol., 390, 2009
2XB1
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BU of 2xb1 by Molmil
Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ...
Authors:Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
7NWJ
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BU of 7nwj by Molmil
Solution NMR structure of the N-terminal domain of CEP164 (1-109)
Descriptor: Centrosomal protein of 164 kDa
Authors:van Breugel, M, Rutherford, T.J.
Deposit date:2021-03-16
Release date:2021-09-15
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
1W09
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BU of 1w09 by Molmil
Solution structure of the cis form of the human alpha-hemoglobin stabilizing protein (AHSP)
Descriptor: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
Authors:Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
Deposit date:2004-05-25
Release date:2004-06-10
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
1W0A
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BU of 1w0a by Molmil
Solution structure of the trans form of the human alpha-hemoglobin stabilizing protein (AHSP)
Descriptor: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
Authors:Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
Deposit date:2004-06-01
Release date:2004-06-10
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
1W0B
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BU of 1w0b by Molmil
Solution structure of the human alpha-hemoglobin stabilizing protein (AHSP) P30A mutant
Descriptor: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
Authors:Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
Deposit date:2004-06-01
Release date:2004-06-10
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
7QCE
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BU of 7qce by Molmil
Crystal structure of an atypical PHD finger of VIN3
Descriptor: DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION
Authors:Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M.
Deposit date:2021-11-23
Release date:2022-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
Descriptor: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-05
Release date:2016-10-12
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
6T8O
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BU of 6t8o by Molmil
Stalled FtsK motor domain bound to dsDNA end
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
Authors:Jean, N.L, Lowe, J.
Deposit date:2019-10-24
Release date:2019-11-20
Last modified:2020-07-01
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8G
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BU of 6t8g by Molmil
Stalled FtsK motor domain bound to dsDNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
Authors:Jean, N.L, Lowe, J.
Deposit date:2019-10-24
Release date:2019-11-20
Last modified:2020-07-01
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8B
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BU of 6t8b by Molmil
FtsK motor domain with dsDNA, translocating state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, MAGNESIUM ION, ...
Authors:Jean, N.L, Lowe, J.
Deposit date:2019-10-24
Release date:2019-11-20
Last modified:2020-07-01
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
2BTH
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BU of 2bth by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
Authors:Ferguson, N, Allen, M.D.
Deposit date:2005-05-31
Release date:2006-05-24
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
2BTG
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BU of 2btg by Molmil
peripheral-subunit binding domains from mesophilic,thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
Descriptor: DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
Authors:Ferguson, N, Allen, M.D.
Deposit date:2005-05-31
Release date:2006-05-24
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
5A7B
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BU of 5a7b by Molmil
Structure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan5211
Descriptor: 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C.
Deposit date:2015-07-03
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere.
Acs Chem.Biol., 10, 2015
5SUY
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BU of 5suy by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction
Descriptor: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-04
Release date:2016-10-12
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5SUZ
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BU of 5suz by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-04
Release date:2016-10-12
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
6S9R
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BU of 6s9r by Molmil
Crystal structure of SSDP from D. melanogaster
Descriptor: Sequence-specific single-stranded DNA-binding protein, isoform A
Authors:Renko, M, Bienz, M.
Deposit date:2019-07-15
Release date:2019-10-09
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019

 

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