2FEJ
Solution structure of human p53 DNA binding domain.
Summary for 2FEJ
| Entry DOI | 10.2210/pdb2fej/pdb |
| Descriptor | Cellular tumor antigen p53, ZINC ION (2 entities in total) |
| Functional Keywords | beta sandwich, transcription |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: Q9NP68 |
| Total number of polymer chains | 1 |
| Total formula weight | 23073.51 |
| Authors | Perez-Canadillas, J.M.,Tidow, H.,Freund, S.M.,Rutherford, T.J.,Ang, H.C.,Fersht, A.R. (deposition date: 2005-12-16, release date: 2006-01-31, Last modification date: 2022-03-09) |
| Primary citation | Perez-Canadillas, J.M.,Tidow, H.,Freund, S.M.,Rutherford, T.J.,Ang, H.C.,Fersht, A.R. Solution structure of p53 core domain: Structural basis for its instability Proc.Natl.Acad.Sci.Usa, 103:2109-2114, 2006 Cited by PubMed: 16461916DOI: 10.1073/pnas.0510941103 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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