2XB1

Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain

Summary for 2XB1

Entry DOI	10.2210/pdb2xb1/pdb
Descriptor	PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ZINC ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	fusion protein, signal transduction, transcription, metal binding, wnt proteins
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus : Q86UU0
Total number of polymer chains	2
Total formula weight	23086.94
Authors	Miller, T.C.,Rutherford, T.J.,Johnson, C.M.,Fiedler, M.,Bienz, M. (deposition date: 2010-04-01, release date: 2010-07-28, Last modification date: 2023-12-20)
Primary citation	Miller, T.C.,Rutherford, T.J.,Johnson, C.M.,Fiedler, M.,Bienz, M. Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor. J.Mol.Biol., 401:969-, 2010 Cited by PubMed: 20637214 DOI: 10.1016/J.JMB.2010.07.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation