4UP5
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN | polymer | 99 | 10537.7 | 1 | UniProt (Q9BRQ0) UniProt (Q86UU0) Pfam (PF00628) | HOMO SAPIENS (HUMAN) | PYGO2, B9L, B-CELL LYMPHOMA 9-LIKE PROTEIN, BCL9-LIKE PROTEIN, PROTEIN BCL9-2 |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | 6-methoxy-1,3-benzothiazol-2-amine | non-polymer | 180.2 | 1 | Chemie (94W) | |||
| 4 | E (A) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 327 - 387 (UniProt: Q9BRQ0)
A: 1235 - 1263 (UniProt: Q86UU0)
| PDB | External Database | Details |
|---|---|---|
| Gly 388 | - | linker |
| Ser 389 | - | linker |
| Gly 390 | - | linker |
| Ser 391 | - | linker |
| Gly 392 | - | linker |
| Ser 393 | - | linker |
| Gly 394 | - | linker |
| Ser 395 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10537.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 311.0 | |
| All* | Total formula weight | 10848.7 |
