PDB: 144 件ウェブページステータス検索Chemie searchBIRD

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7EA8	Human SETD2 bound to a nucleosome containing oncohistone mutations 分子名称: 601-DNA, Histone H2A type 1-D, Histone H2B type 2-E, ... 著者 Jing, H, Liu, Y. 登録日 2021-03-06 公開日 2021-07-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations. Cell Discov, 7, 2021
5BNV	Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer 分子名称: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ... 著者 Huang, H, Patel, D.J. 登録日 2015-05-26 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.795 Å) 主引用文献 A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nat.Struct.Mol.Biol., 22, 2015
7CJ0	Crystal structure of DNAJC9 HBD in complex with H3.3-H4 dimer and MCM2 HBD 分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, GLYCEROL, ... 著者 Bao, H, Huang, H. 登録日 2020-07-09 公開日 2021-04-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network. Mol.Cell, 81, 2021
7CIZ	Crystal structure of DNAJC9 HBD helix2 in complex with H3.3-H4 dimer and MCM2 HBD 分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, Histone H3.3, ... 著者 Bao, H, Huang, H. 登録日 2020-07-08 公開日 2021-04-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network. Mol.Cell, 81, 2021
5B32	The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. 登録日 2016-02-08 公開日 2016-08-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
5B33	The crystal structure of the H2AZ nucleosome with H3.3. 分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... 著者 Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. 登録日 2016-02-08 公開日 2016-08-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.925 Å) 主引用文献 Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
7VCQ	structure of viral protein BKRF4 in complex with H3.3-H4-ASF1 分子名称: Histone H3.3, Histone H4, Histone chaperone ASF1B, ... 著者 Liu, Y.R. 登録日 2021-09-03 公開日 2022-08-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone. J.Mol.Biol., 434, 2022
4Z5T	The nucleosome containing human H3.5 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H. 登録日 2015-04-03 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin, 9, 2016
4QQ4	CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3 分子名称: CHLORIDE ION, Histone H3.3, MORC family CW-type zinc finger protein 3, ... 著者 Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-06-26 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins. J.Biol.Chem., 291, 2016
6PZV	Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin 分子名称: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ... 著者 Ren, W, Song, J. 登録日 2019-08-01 公開日 2020-07-15 最終更新日 2020-08-12 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation. Proc.Natl.Acad.Sci.USA, 117, 2020
2L43	Structural basis for histone code recognition by BRPF2-PHD1 finger 分子名称: Histone H3.3,LINKER,Bromodomain-containing protein 1, ZINC ION 著者 Qin, S, Zhang, J, Wu, J, Shi, Y. 登録日 2010-10-01 公開日 2011-08-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF To be Published
2RHU	Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine and in chimera with histone H3.3(28-34) 分子名称: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, N-DIMETHYL-LYSINE, ... 著者 Li, H, Patel, D.J. 登録日 2007-10-09 公開日 2007-12-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28, 2007
6A5O	RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (9.9 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6U04	Crystal structure of human BRPF1 PZP bound to histone H3 tail 分子名称: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ... 著者 Klein, B.J, Kutateladze, T.G. 登録日 2019-08-13 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin. Structure, 28, 2020
7A08	CryoEM Structure of cGAS Nucleosome complex 分子名称: Cyclic GMP-AMP synthase, Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, ... 著者 Michalski, S, de Oliveira Mann, C.C, Witte, G, Bartho, J, Lammens, K, Hopfner, K.P. 登録日 2020-08-07 公開日 2020-09-23 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Structural basis for sequestration and autoinhibition of cGAS by chromatin. Nature, 587, 2020
6R0C	Human-D02 Nucleosome Core Particle with biotin-streptavidin label 分子名称: DNA (142-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ... 著者 Pye, V.E, Wilson, M.D, Cherepanov, P, Costa, A. 登録日 2019-03-12 公開日 2019-09-25 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer. Nat Commun, 10, 2019
6RNY	PFV intasome - nucleosome strand transfer complex 分子名称: DNA (108-MER), DNA (128-MER), DNA (33-MER), ... 著者 Pye, V.E, Renault, L, Maskell, D.P, Cherepanov, P, Costa, A. 登録日 2019-05-09 公開日 2019-09-25 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer. Nat Commun, 10, 2019
1PDQ	Polycomb chromodomain complexed with the histone H3 tail containing trimethyllysine 27. 分子名称: Histone H3.3, Polycomb protein 著者 Fischle, W, Wang, Y, Jacobs, S.A, Kim, Y, Allis, C.D, Khorasanizadeh, S. 登録日 2003-05-20 公開日 2003-08-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains Genes Dev., 17, 2003
8PKI	Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 分子名称: DNA, Histone H2A, Histone H2B type 1-C/E/G, ... 著者 Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. 登録日 2023-06-26 公開日 2024-02-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 31, 2024
4O62	CW-type zinc finger of ZCWPW2 in complex with the amino terminus of histone H3 分子名称: Histone H3.3, UNKNOWN ATOM OR ION, ZINC ION, ... 著者 Liu, Y, Tempel, W, Dong, A, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-20 公開日 2014-03-26 最終更新日 2016-06-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins. J.Biol.Chem., 291, 2016
3ASK	Structure of UHRF1 in complex with histone tail 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION 著者 Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. 登録日 2010-12-16 公開日 2012-01-25 最終更新日 2013-06-05 実験手法 X-RAY DIFFRACTION (2.904 Å) 主引用文献 Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4W5A	Complex structure of ATRX ADD bound to H3K9me3S10ph peptide 分子名称: Peptide from Histone H3.3, Transcriptional regulator ATRX, ZINC ION 著者 Zhao, D, Xiang, B, Li, H. 登録日 2014-08-17 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons Proc.Natl.Acad.Sci.USA, 112, 2015
7OKP	Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Histone H3.3, Histone-arginine methyltransferase CARM1, ... 著者 Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. 登録日 2021-05-18 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors. Chembiochem, 22, 2021
3JVK	Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, histone H3.3 peptide 著者 Vollmuth, F, Blankenfeldt, W, Geyer, M. 登録日 2009-09-17 公開日 2009-10-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution J.Biol.Chem., 284, 2009

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