PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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6XA1	Structure of a drug-like compound stalled human translation termination complex 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J. 登録日 2020-06-03 公開日 2020-10-07 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Selective inhibition of human translation termination by a drug-like compound. Nat Commun, 11, 2020
6AHD	The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-17 公開日 2018-11-14 最終更新日 2021-06-30 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
6ZME	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-02 公開日 2020-08-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
8OJ0	60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. 登録日 2023-03-23 公開日 2024-02-21 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
8H6K	Cryo-EM structure of human exon-defined spliceosome in the mature B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6L	Cryo-EM structure of human exon-defined spliceosome in the early B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8PPL	MERS-CoV Nsp1 bound to the human 43S pre-initiation complex 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. 登録日 2023-07-07 公開日 2023-10-18 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-15 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
5WYK	Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... 著者 Ye, K, Zhu, X, Sun, Q. 登録日 2017-01-13 公開日 2017-03-29 最終更新日 2017-05-17 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Molecular architecture of the 90S small subunit pre-ribosome. Elife, 6, 2017
6ZMW	Structure of a human 48S translational initiation complex 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. 登録日 2020-07-04 公開日 2020-09-23 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of a human 48Stranslational initiation complex. Science, 369, 2020
7QVP	Human collided disome (di-ribosome) stalled on XBP1 mRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Denk, T.G, Tesina, P, Beckmann, R. 登録日 2022-01-22 公開日 2022-10-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nat Commun, 13, 2022
6ZMI	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-02 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZM7	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-01 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6QW6	Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-05 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
5WYJ	Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... 著者 Ye, K, Zhu, X, Sun, Q. 登録日 2017-01-13 公開日 2017-03-29 最終更新日 2019-10-09 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Molecular architecture of the 90S small subunit pre-ribosome. Elife, 6, 2017
8OZ0	Structure of a human 48S translation initiation complex with eIF4F and eIF4A 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V. 登録日 2023-05-06 公開日 2024-02-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A. Nat.Struct.Mol.Biol., 31, 2024
6Y57	Structure of human ribosome in hybrid-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-25 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6HCQ	Structure of the rabbit collided di-ribosome (collided monosome) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. 登録日 2018-08-16 公開日 2018-10-17 最終更新日 2018-11-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
5A2Q	Structure of the HCV IRES bound to the human ribosome 分子名称: 18S RRNA, HCV IRES, MAGNESIUM ION, ... 著者 Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. 登録日 2015-05-21 公開日 2015-07-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
6QDV	Human post-catalytic P complex spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. 登録日 2019-01-03 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
6Y0G	Structure of human ribosome in classical-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-07 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
7A09	Structure of a human ABCE1-bound 43S pre-initiation complex - State III 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-08-07 公開日 2020-10-14 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
5BUD	Crystal structure of Candida albicans Rai1 in complex with pU5-Mn2+ 分子名称: Decapping nuclease RAI1, MANGANESE (II) ION, RNA (5'-R(P*UP*UP*UP*U)-3') 著者 Wang, V.Y, Tong, L. 登録日 2015-06-03 公開日 2015-07-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Res., 43, 2015

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