PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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2QCM	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP 分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCN	Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP 分子名称: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ... 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCO	Crystal structure of the transcriptional regulator CmeR from Campylobacter jejuni 分子名称: CmeR, GLYCEROL 著者 Gu, R, Su, C, Shi, F, Li, M, McDermott, G, Zhang, Q, Yu, E.W. 登録日 2007-06-19 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of the transcriptional regulator CmeR from Campylobacter jejuni. J.Mol.Biol., 372, 2007
2QCP	1.0 A Structure of CusF-Ag(I) residues 10-88 from Escherichia coli 分子名称: Cation efflux system protein cusF, NITRATE ION, SILVER ION, ... 著者 Loftin, I.R. 登録日 2007-06-19 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Unusual Cu(I)/Ag(I) coordination of Escherichia coli CusF as revealed by atomic resolution crystallography and X-ray absorption spectroscopy Protein Sci., 16, 2007
2QCQ	Crystal structure of Bone Morphogenetic Protein-3 (BMP-3) 分子名称: Bone morphogenetic protein 3 著者 Allendorph, G.P. 登録日 2007-06-19 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors. Biochemistry, 46, 2007
2QCS	A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell(Cambridge,Mass.), 130, 2007
2QCT	Structure of Lyp with inhibitor I-C11 分子名称: 1,2-ETHANEDIOL, 6-HYDROXY-3-{(4R)-1-[4-(1-NAPHTHYLAMINO)-4-OXOBUTYL]-1,2,3-TRIAZOLIDIN-4-YL}-1-BENZOFURAN-5-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 22 著者 Yu, X, Sun, J.P, Zhang, Z.Y. 登録日 2007-06-19 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of Lyp and its complex with a selective inhibitor To be Published
2QCU	Crystal structure of Glycerol-3-phosphate Dehydrogenase from Escherichia coli 分子名称: 1,2-ETHANEDIOL, Aerobic glycerol-3-phosphate dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Yeh, J.I, Chinte, U, Du, S. 登録日 2007-06-19 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism. Proc.Natl.Acad.Sci.Usa, 105, 2008
2QCV	CRYSTAL STRUCTURE OF a putative 5-dehydro-2-deoxygluconokinase (IOLC) FROM BACILLUS HALODURANS C-125 AT 1.90 A RESOLUTION 分子名称: Putative 5-dehydro-2-deoxygluconokinase, TRIETHYLENE GLYCOL 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-06-19 公開日 2007-08-07 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a putative 5-dehydro-2-deoxygluconokinase (NP_243185.1) from Bacillus halodurans at 1.90 A resolution To be published
2QCW	Crystal Structure of Bone Morphogenetic Protein-6 (BMP-6) 分子名称: Bone morphogenetic protein 6 著者 Allendorph, G.P. 登録日 2007-06-19 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors. Biochemistry, 46, 2007
2QCX	Crystal structure of Bacillus subtilis TenA Y112F mutant complexed with formyl aminomethyl pyrimidine 分子名称: N-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-N-(2-HYDROXYETHYL)FORMAMIDE, Transcriptional activator tenA 著者 Zhang, Y, Jenkins, A.L, Begley, T.P, Ealick, S.E. 登録日 2007-06-19 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutagenesis studies on TenA: A thiamin salvage enzyme from Bacillus subtilis Bioorg.Chem., 36, 2008
2QCY	Crystal Structure of a monomeric form of Severe Acute Respiratory Syndrome (SARS) 3C-like protease mutant 分子名称: 3C-like proteinase 著者 Shi, J.H, Sivaraman, J, Song, J.X. 登録日 2007-06-20 公開日 2008-03-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease. J.Virol., 82, 2008
2QCZ	Structure of N-terminal domain of E. Coli YaeT 分子名称: Outer membrane protein assembly factor yaeT 著者 Kim, S, Malinverni, J.C, Sliz, P, Silhavy, T.J, Harrison, S.C, Kahne, D. 登録日 2007-06-20 公開日 2007-08-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of an essential component of the outer membrane protein assembly machine. Science, 317, 2007
2QD0	Crystal structure of mitoNEET 分子名称: FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH domain-containing protein 1 著者 Lin, J, Zhou, T, Ye, K, Wang, J. 登録日 2007-06-20 公開日 2007-08-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins. Proc.Natl.Acad.Sci.Usa, 104, 2007
2QD1	2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound 分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... 著者 Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. 登録日 2007-06-20 公開日 2007-10-30 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
2QD2	F110A variant of human ferrochelatase with protoheme bound 分子名称: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilota, W.N. 登録日 2007-06-20 公開日 2007-10-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
2QD3	Wild type human ferrochelatase crystallized with ammonium sulfate 分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... 著者 Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. 登録日 2007-06-20 公開日 2007-10-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
2QD4	Wild type human ferrochelatase crystallized with MnCl2 分子名称: CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. 登録日 2007-06-20 公開日 2007-10-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
2QD5	Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound 分子名称: ACETIC ACID, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Meldock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. 登録日 2007-06-20 公開日 2007-10-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
2QD6	HIV-1 Protease Mutant I50V with potent Antiviral inhibitor GRL-98065 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, ACETATE ION, CHLORIDE ION, ... 著者 Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T. 登録日 2007-06-20 公開日 2008-04-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J.Med.Chem., 50, 2007
2QD7	HIV-1 Protease Mutant V82A with potent Antiviral inhibitor GRL-98065 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T. 登録日 2007-06-20 公開日 2008-04-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J.Med.Chem., 50, 2007
2QD8	HIV-1 Protease Mutant I84V with potent Antiviral inhibitor GRL-98065 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, ACETATE ION, CHLORIDE ION, ... 著者 Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T. 登録日 2007-06-20 公開日 2008-04-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J.Med.Chem., 50, 2007
2QD9	P38 Alpha Map Kinase inhibitor based on heterobicyclic scaffolds 分子名称: 1-[5-[[3-[2,4-bis(fluoranyl)phenyl]-6,8-dihydro-5~{H}-imidazo[1,5-a]pyrazin-7-yl]carbonyl]-6-methoxy-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-2-[(3~{R})-3-oxidanylpyrrolidin-1-yl]ethane-1,2-dione, Mitogen-activated protein kinase 14 著者 Sack, J.S. 登録日 2007-06-20 公開日 2007-08-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Synthesis and SAR of p38alpha MAP kinase inhibitors based on heterobicyclic scaffolds. Bioorg.Med.Chem.Lett., 17, 2007
2QDB	Crystal structure of staphylococcal nuclease variant E75Q/D21N/T33V/T41I/S59A/P117G/S128A at 100 K 分子名称: PHOSPHATE ION, Thermonuclease 著者 Baran, K.L, Schlessman, J.L, Garcia-Moreno, B.E. 登録日 2007-06-20 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Electrostatic effects in a network of polar and ionizable groups in staphylococcal nuclease. J.Mol.Biol., 379, 2008
2QDC	Crystal structure of the HePTP catalytic domain D236A mutant 分子名称: GLYCEROL, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 7 著者 Critton, D.A, Tortajada, A, Page, R. 登録日 2007-06-20 公開日 2008-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of substrate recognition by hematopoietic tyrosine phosphatase. Biochemistry, 47, 2008

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