2QCT

Structure of Lyp with inhibitor I-C11

Summary for 2QCT

• Entry DOI: 10.2210/pdb2qct/pdb
• Related: 2QCJ
• Descriptor: Tyrosine-protein phosphatase non-receptor type 22, 6-HYDROXY-3-{(4R)-1-[4-(1-NAPHTHYLAMINO)-4-OXOBUTYL]-1,2,3-TRIAZOLIDIN-4-YL}-1-BENZOFURAN-5-CARBOXYLIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: ptpn22, lyp, ptp, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q9Y2R2
• Total number of polymer chains: 2
• Total formula weight: 74102.88

Authors

Yu, X.,Sun, J.P.,Zhang, Z.Y. (deposition date: 2007-06-19, release date: 2007-11-20, Last modification date: 2023-08-30)

• Primary citation: Yu, X.,Sun, J.P.,He, Y.T.,Zhou, B.,Liu, S.J.,Zhang, Z.Y.; Crystal structure of Lyp and its complex with a selective inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)