2QCT
Structure of Lyp with inhibitor I-C11
Summary for 2QCT
Entry DOI | 10.2210/pdb2qct/pdb |
Related | 2QCJ |
Descriptor | Tyrosine-protein phosphatase non-receptor type 22, 6-HYDROXY-3-{(4R)-1-[4-(1-NAPHTHYLAMINO)-4-OXOBUTYL]-1,2,3-TRIAZOLIDIN-4-YL}-1-BENZOFURAN-5-CARBOXYLIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ptpn22, lyp, ptp, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q9Y2R2 |
Total number of polymer chains | 2 |
Total formula weight | 74102.88 |
Authors | Yu, X.,Sun, J.P.,Zhang, Z.Y. (deposition date: 2007-06-19, release date: 2007-11-20, Last modification date: 2023-08-30) |
Primary citation | Yu, X.,Sun, J.P.,He, Y.T.,Zhou, B.,Liu, S.J.,Zhang, Z.Y. Crystal structure of Lyp and its complex with a selective inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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