2QD2

F110A variant of human ferrochelatase with protoheme bound

Summary for 2QD2

Entry DOI	10.2210/pdb2qd2/pdb
Descriptor	Ferrochelatase, BICARBONATE ION, FE2/S2 (INORGANIC) CLUSTER, ... (7 entities in total)
Functional Keywords	heme synthesis, ferrochelatase, protoporphyrin ix, heme biosynthesis, iron, lyase, porphyrin biosynthesis, biosynthetic protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	85752.76
Authors	Medlock, A.E.,Dailey, T.A.,Ross, T.A.,Dailey, H.A.,Lanzilota, W.N. (deposition date: 2007-06-20, release date: 2007-10-30, Last modification date: 2024-02-21)
Primary citation	Medlock, A.E.,Dailey, T.A.,Ross, T.A.,Dailey, H.A.,Lanzilotta, W.N. A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373:1006-1016, 2007 Cited by PubMed: 17884090 DOI: 10.1016/j.jmb.2007.08.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation