2QD2
F110A variant of human ferrochelatase with protoheme bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ferrochelatase | polymer | 359 | 41102.3 | 2 | UniProt (Q7KZA3) Pfam (PF00762) UniProt (by SIFTS) (P22830) | Homo sapiens (human) | |
| 2 | C, J (A, B) | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 3 | D, K (A, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 4 | E, F, L (A, B) | IMIDAZOLE | non-polymer | 69.1 | 3 | Chemie (IMD) | |||
| 5 | G, H, M, N (A, B) | CHOLIC ACID | non-polymer | 408.6 | 4 | Chemie (CHD) | |||
| 6 | I, O (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 7 | P, Q (A, B) | water | water | 18.0 | 385 | Chemie (HOH) |
Sequence modifications
A, B: 65 - 423 (UniProt: Q7KZA3)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Phe 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82204.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3548.2 | |
| All* | Total formula weight | 85752.8 |
