2QD5
Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound
Summary for 2QD5
Entry DOI | 10.2210/pdb2qd5/pdb |
Related | 2QD1 2QD3 2QD4 |
Descriptor | Ferrochelatase, LEAD (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... (9 entities in total) |
Functional Keywords | heme synthesis, ferrochelatase, protoporphyrin ix, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P22830 |
Total number of polymer chains | 2 |
Total formula weight | 86186.66 |
Authors | Meldock, A.E.,Dailey, T.A.,Ross, T.A.,Dailey, H.A.,Lanzilotta, W.N. (deposition date: 2007-06-20, release date: 2007-10-30, Last modification date: 2024-02-21) |
Primary citation | Medlock, A.E.,Dailey, T.A.,Ross, T.A.,Dailey, H.A.,Lanzilotta, W.N. A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373:1006-1016, 2007 Cited by PubMed: 17884090DOI: 10.1016/j.jmb.2007.08.040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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