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2QD5

Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ferrochelatasepolymer35941178.42UniProt (P22830)
Pfam (PF00762)
Homo sapiens (human)Protoheme ferro-lyase, Heme synthetase
2C, K
(A, B)
LEAD (II) IONnon-polymer207.22Chemie (PB)
PubChem (73212)
3D, L
(A, B)
FE2/S2 (INORGANIC) CLUSTERnon-polymer175.82Chemie (FES)
4E, F, M, N
(A, B)
CHOLIC ACIDnon-polymer408.64Chemie (CHD)
PubChem (16401672)
PubChem (16758100)
PubChem (18528842)
PubChem (20638765)
PubChem (303)
PubChem (23636694)
PubChem (23640631)
PubChem (6676)
PubChem (23876184)
PubChem (24836753)
PubChem (24883735)
PubChem (43835083)
PubChem (16401251)
PubChem (44135469)
PubChem (44629918)
PubChem (44657327)
PubChem (21139644)
PubChem (45114537)
PubChem (45382168)
PubChem (122340)
PubChem (1762378)
PubChem (46397523)
PubChem (46783697)
PubChem (49791911)
PubChem (49796810)
PubChem (50989873)
PubChem (51432410)
PubChem (51546373)
PubChem (53298695)
PubChem (53393606)
PubChem (53477699)
PubChem (160636)
PubChem (221493)
PubChem (57937243)
PubChem (44339334)
PubChem (58133002)
PubChem (58582306)
PubChem (376829)
PubChem (439520)
PubChem (58984417)
PubChem (59032051)
PubChem (59316662)
PubChem (59877711)
PubChem (59963674)
PubChem (59997751)
PubChem (60076012)
PubChem (60098994)
PubChem (60114995)
PubChem (440427)
PubChem (46780112)
PubChem (66678354)
PubChem (68097396)
PubChem (68131418)
PubChem (68318251)
PubChem (68338620)
PubChem (68372213)
PubChem (71260265)
PubChem (70649328)
PubChem (70824975)
PubChem (70930320)
PubChem (70930789)
PubChem (70960845)
PubChem (637625)
PubChem (59130005)
PubChem (59381614)
PubChem (59903914)
PubChem (67122255)
PubChem (3246132)
PubChem (69904012)
PubChem (130213)
PubChem (145883)
PubChem (70866085)
PubChem (71001249)
PubChem (239672)
PubChem (71314856)
PubChem (71752895)
PubChem (5283869)
PubChem (5283870)
PubChem (5283871)
PubChem (5283873)
PubChem (5283875)
PubChem (5283877)
PubChem (5283878)
PubChem (74765127)
PubChem (89830646)
PubChem (5302608)
PubChem (5315844)
PubChem (91128541)
PubChem (91810856)
PubChem (5283876)
PubChem (5283879)
PubChem (5283880)
PubChem (5283872)
PubChem (5283874)
PubChem (98044963)
PubChem (99565617)
PubChem (122645815)
PubChem (124161889)
PubChem (124318072)
PubChem (124488681)
PubChem (125037036)
PubChem (126577457)
PubChem (129274856)
PubChem (129274855)
PubChem (129359810)
PubChem (6708709)
PubChem (6850901)
PubChem (6850905)
PubChem (99564899)
PubChem (99565857)
PubChem (133135020)
PubChem (133126746)
PubChem (11350342)
PubChem (117684834)
PubChem (117767695)
PubChem (117944573)
PubChem (118241311)
PubChem (9802771)
PubChem (121232934)
PubChem (9846429)
PubChem (9866174)
PubChem (122537896)
PubChem (122537897)
PubChem (122644681)
PubChem (122644923)
PubChem (122646384)
PubChem (12303168)
PubChem (13020196)
PubChem (71172094)
PubChem (124328806)
PubChem (124364505)
PubChem (124425250)
PubChem (124488680)
PubChem (124511215)
PubChem (124518077)
PubChem (124518078)
PubChem (124518446)
PubChem (124761950)
PubChem (12080557)
PubChem (12303167)
PubChem (12303172)
PubChem (12303175)
PubChem (12303178)
PubChem (12303180)
PubChem (13020205)
PubChem (124841930)
PubChem (124896923)
PubChem (124896924)
PubChem (124896925)
PubChem (124896926)
PubChem (124904187)
PubChem (124904188)
PubChem (124906682)
PubChem (124906683)
PubChem (124914603)
PubChem (124914604)
PubChem (124914605)
PubChem (124914606)
PubChem (125027431)
PubChem (125037037)
PubChem (162771689)
PubChem (163059393)
PubChem (163059399)
PubChem (163059389)
PubChem (126422551)
PubChem (126422552)
PubChem (126577461)
PubChem (126672319)
PubChem (166858402)
PubChem (126969154)
PubChem (129106816)
PubChem (129460958)
PubChem (129600748)
PubChem (129628082)
PubChem (130220803)
PubChem (131700165)
PubChem (132441695)
PubChem (133548348)
PubChem (133612061)
PubChem (133655733)
PubChem (133687870)
PubChem (133688934)
PubChem (134462403)
PubChem (134555902)
PubChem (134866321)
PubChem (135373095)
PubChem (137474142)
PubChem (138107312)
PubChem (139248576)
PubChem (139291795)
PubChem (139372812)
PubChem (140618124)
PubChem (141854542)
PubChem (142134118)
PubChem (143658950)
PubChem (144316980)
PubChem (145264188)
PubChem (145714625)
PubChem (146030145)
PubChem (146665897)
PubChem (154033190)
PubChem (154036252)
PubChem (154747009)
PubChem (154825357)
PubChem (155275443)
PubChem (155605940)
PubChem (157048615)
PubChem (157269375)
PubChem (157351909)
PubChem (157383333)
PubChem (158041002)
PubChem (158420924)
PubChem (158675416)
PubChem (160081178)
PubChem (160743345)
PubChem (160917187)
PubChem (161973449)
PubChem (163059390)
PubChem (163059391)
PubChem (163059392)
PubChem (163059394)
PubChem (163059395)
PubChem (163059396)
PubChem (163059397)
PubChem (163059398)
PubChem (163059400)
PubChem (163452349)
PubChem (163452350)
PubChem (163452351)
PubChem (167344826)
PubChem (168841979)
PubChem (168841990)
PubChem (168845540)
PubChem (169410142)
PubChem (169436432)
PubChem (171721516)
PubChem (157060709)
5G, O
(A, B)
PROTOPORPHYRIN IXnon-polymer562.72Chemie (PP9)
6H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
7I, J, Q
(A, B)
ACETIC ACIDnon-polymer60.13Chemie (ACY)
8P
(B)
OXYGEN MOLECULEnon-polymer32.01Chemie (OXY)
PubChem (977)
9R, S
(A, B)
waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82356.8
Non-Polymers*Number of molecules15
Total formula weight3829.9
All*Total formula weight86186.7
*Water molecules are not included.

253091

PDB entries from 2026-05-06

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