PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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2FSH	Complex SecA:AMP-PNP from Escherichia coli 分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Preprotein translocase secA subunit 著者 Papanikolau, Y, Petratos, K, Economou, A. 登録日 2006-01-23 公開日 2007-01-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of dimeric SecA, the Escherichia coli preprotein translocase motor. J.Mol.Biol., 366, 2007
4UUX	Competence or damage-inducible protein CinA from Thermus thermophilus 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CINA, MAGNESIUM ION, ... 著者 Derrick, J, Karuppiah, V. 登録日 2014-07-31 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure and Mechanism of the Bifunctional Cina Enzyme from Thermus Thermophilus J.Biol.Chem., 289, 2014
4UVP	Crystal structure of human tankyrase 2 in complex with 5-amino-3- ethyl-1,2-dihydroisoquinolin-1-one 分子名称: 5-amino-3-ethylisoquinolin-1(2H)-one, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2014-08-07 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
4UWF	Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one: a Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors 分子名称: (8S)-9-[3,5-bis(fluoranyl)phenyl]-2-morpholin-4-yl-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 著者 Pasquier, B, El-Ahmad, Y, Filoche-Romme, B, Dureuil, C, Fassy, F, Abecassis, P.Y, Mathieu, M, Bertrand, T, Benard, T, Barriere, C, ElBatti, S, Letallec, J.P, Sonnefraud, V, Brollo, M, Delbarre, L, Loyau, V, Pilorge, F, Bertin, L, Richepin, P, Arigon, J, Labrosse, J.R, Clement, J, Durand, F, Combet, R, Perraut, P, Leroy, V, Gay, F, Lefrancois, D, Bretin, F, Marquette, J.P, Michot, N, Caron, A, Castell, C, Schio, L, McCort, G, Goulaouic, H, Garcia-Echeverria, C, Ronan, B. 登録日 2014-08-12 公開日 2014-11-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Discovery of (2S)-8-[(3R)-3-Methylmorpholin-4-Yl]-1-(3-Methyl-2-Oxobutyl)-2-(Trifluoromethyl)-3,4-Dihydro-2H-Pyrimido[1,2-A]Pyrimidin-6-One: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors. J.Med.Chem., 58, 2015
4UZV	Structure of a triple mutant of ASV-TfTrHb 分子名称: ACETATE ION, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE 著者 Baiocco, P, Bonamore, A, Sciamanna, N, Ilari, A, Boechi, L, Boffi, A, Smulevich, G, Feis, A. 登録日 2014-09-09 公開日 2014-09-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Role of Local Structure and Dynamics of Small Ligand Migration in Proteins: A Study of a Mutated Truncated Hemoprotein from Thermobifida Fusca by Time Resolved Mir Spectroscopy. J.Phys.Chem.B, 118, 2014
2FUL	Crystal Structure of the C-terminal Domain of S. cerevisiae eIF5 分子名称: Eukaryotic translation initiation factor 5, SULFATE ION 著者 Wei, Z, Xue, Y, Xu, H, Gong, W. 登録日 2006-01-27 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the C-terminal Domain of S.cerevisiae eIF5 J.Mol.Biol., 359, 2006
5K2G	Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED 分子名称: Eukaryotic peptide chain release factor GTP-binding subunit 著者 Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S. 登録日 2016-05-18 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 ELECTRON CRYSTALLOGRAPHY (1.1 Å) 主引用文献 Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc.Natl.Acad.Sci.USA, 113, 2016
4UQF	CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES GTP CYCLOHYDROLASE I 分子名称: GTP cyclohydrolase 1 著者 Schuessler, S, Perbandt, M, Fischer, M, Graewert, T. 登録日 2014-06-23 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of GTP cyclohydrolase I from Listeria monocytogenes, a potential anti-infective drug target. Acta Crystallogr.,Sect.F, 75, 2019
4UWY	FGFR1 Apo structure 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FIBROBLAST GROWTH FACTOR RECEPTOR 1 著者 Thiyagarajan, N, Bunney, T, Katan, M. 登録日 2014-08-15 公開日 2015-02-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine, 2, 2015
4UXZ	Structure of delta7-DgkA-syn in 7.9 MAG to 2.18 angstrom resolution 分子名称: (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ACETATE ION, ... 著者 Li, D, Howe, N, Caffrey, M. 登録日 2014-08-27 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase. Nat.Commun., 6, 2015
4UZE	R66A mutant of FAD synthetase from Corynebacterium ammoniagenes 分子名称: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION 著者 Martinez-Julvez, M, Herguedas, B, Milagros, M. 登録日 2014-09-05 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Quaternary Organization in a Bifunctional Prokaryotic Fad Synthetase: Involvement of an Arginine at its Adenylyltransferase Module on the Riboflavin Kinase Activity. Biochim.Biophys.Acta, 1854, 2015
4UWS	VIM-26-PEG. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding. 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, METALLO-BETA-LACTAMASE VIM-26, ... 著者 Leiros, H.-K.S, Edvardsen, K.S.W, Bjerga, G.E.K, Samuelsen, O. 登録日 2014-08-14 公開日 2015-02-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural and Biochemical Characterization of Vim-26 Show that Leu224 Has Implications for the Substrate Specificity of Vim Metallo-Beta-Lactamases. FEBS J., 282, 2015
2G0D	Nisin cyclase 分子名称: Nisin biosynthesis protein nisC, ZINC ION 著者 Nair, S.K. 登録日 2006-02-12 公開日 2006-05-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis Science, 311, 2006
4V6Z	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V77	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post2b) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
2FYU	Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor 分子名称: (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE, Cytochrome b, Cytochrome c1, ... 著者 Xia, D, Esser, L. 登録日 2006-02-08 公開日 2006-08-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex. Proc.Natl.Acad.Sci.Usa, 103, 2006
6DKU	Crystal structure of Myotis VP35 mutant of interferon inhibitory domain 分子名称: VP35 著者 Liu, H, Ginell, G.M, Keefe, L.J, Leung, D.W, Amarasinghe, G.K. 登録日 2018-05-30 公開日 2018-07-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes. Cell Rep, 24, 2018
2G4F	Structure of S.olivaceoviridis xylanase Q88A/R275A mutant 分子名称: Hydrolase 著者 Diertavitian, S, Kaneko, S, Fujimoto, Z, Kuno, A, Johansson, E, Lo Leggio, L. 登録日 2006-02-22 公開日 2007-03-06 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-based engineering of glucose specificity in a family 10 xylanase from Streptomyces olivaceoviridis E-86 PROCESS BIOCHEM, 47, 2012
6DLS	PRPP Riboswitch bound to PRPP, thallium acetate soaked structure 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PRPP Riboswitch, ... 著者 Peselis, A, Serganov, A. 登録日 2018-06-02 公開日 2018-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.885 Å) 主引用文献 ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
6DDI	Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue 分子名称: 1,2-ETHANEDIOL, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, Bromodomain-containing protein 2, ... 著者 White, S.W, Yun, M. 登録日 2018-05-10 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer. Cancer Res., 80, 2020
4V7K	Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. 登録日 2009-11-02 公開日 2014-07-09 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
6DP4	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 20 mM Mg2+ and 75 mM K+ for 40 s at 21 C 分子名称: 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.374 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
4W5T	The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-7 分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2014-08-18 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Gene regulation. Structural basis for microRNA targeting. Science, 346, 2014
6DF2	Improved anti-phosphotyrosine antibody 4G10-S5-4D5 Fab complexed with phosphotyrosine peptide 分子名称: Anti-phosphotyrosine antibody c310-4D5 heavy chain, Anti-phosphotyrosine antibody c310-4D5 light chain, LEU-PTR-LEU 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
4W69	Crystal Structure of Full-Length Split GFP Mutant Q157C Disulfide Dimer, P 43 21 2 Space Group 分子名称: fluorescent protein Q157C 著者 Leibly, D.J, Waldo, G.S, Yeates, T.O. 登録日 2014-08-20 公開日 2015-02-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.975 Å) 主引用文献 A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015

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