7BAG

C3b in complex with CP40

Summary for 7BAG

Entry DOI	10.2210/pdb7bag/pdb
Descriptor	Complement C3, Compstatin CP40, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	complement system, c3b, c3 convertase, inhibitor, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	178330.76
Authors	Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Sfyroera, G.,Gros, P.,Lambris, J.,Ricklin, D. (deposition date: 2020-12-15, release date: 2022-01-12, Last modification date: 2024-02-07)
Primary citation	Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Berger, N.,Sfyroera, G.,Gros, P.,Lambris, J.D.,Ricklin, D. Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors. Nat Commun, 13:5519-5519, 2022 Cited by PubMed: 36127336 DOI: 10.1038/s41467-022-33003-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation