2R6K

Crystal structure of an I71V hGSTA1-1 mutant in complex with S-hexylglutathione

Summary for 2R6K

Entry DOI	10.2210/pdb2r6k/pdb
Descriptor	Glutathione S-transferase A1, S-HEXYLGLUTATHIONE (3 entities in total)
Functional Keywords	human alpha class glutathione transferase 1-1, s-hexyl-glutathione, x-ray crystal structure, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P08263
Total number of polymer chains	2
Total formula weight	52097.17
Authors	Dirr, H.W.,Fisher, L.,Burke, J.P.W.G.,Sayed, M.,Sewell, T. (deposition date: 2007-09-06, release date: 2008-08-19, Last modification date: 2023-08-30)
Primary citation	Achilonu, I.,Gildenhuys, S.,Fisher, L.,Burke, J.,Fanucchi, S.,Sewell, B.T.,Fernandes, M.,Dirr, H.W. The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function. Acta Crystallogr.,Sect.F, 66:776-780, 2010 Cited by PubMed: 20606271 DOI: 10.1107/S1744309110019135 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation