2R5N

Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate

Summary for 2R5N

Entry DOI	10.2210/pdb2r5n/pdb
Related	1QGD 2R8O 2R8P
Descriptor	Transketolase 1, RIBOSE-5-PHOSPHATE, CALCIUM ION, ... (7 entities in total)
Functional Keywords	thiamin catalysis, sugar phosphates, acceptor, near attack conformation, cyclic, acyclic, ribose-5-phospate, pyranose, metal-binding, thiamine pyrophosphate, transferase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	148857.22
Authors	Parthier, C.,Asztalos, P.,Wille, G.,Tittmann, K. (deposition date: 2007-09-04, release date: 2007-11-06, Last modification date: 2023-08-30)
Primary citation	Asztalos, P.,Parthier, C.,Golbik, R.,Kleinschmidt, M.,Hubner, G.,Weiss, M.S.,Friedemann, R.,Wille, G.,Tittmann, K. Strain and Near Attack Conformers in Enzymic Thiamin Catalysis: X-ray Crystallographic Snapshots of Bacterial Transketolase in Covalent Complex with Donor Ketoses Xylulose 5-phosphate and Fructose 6-phosphate, and in Noncovalent Complex with Acceptor Aldose Ribose 5-phosphate. Biochemistry, 46:12037-12052, 2007 Cited by PubMed: 17914867 DOI: 10.1021/bi700844m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation