2R8P
Transketolase from E. coli in complex with substrate D-fructose-6-phosphate
Summary for 2R8P
Entry DOI | 10.2210/pdb2r8p/pdb |
Related | 1QGD 2R5N 2R8O |
Descriptor | Transketolase 1, CALCIUM ION, 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol, ... (5 entities in total) |
Functional Keywords | reaction intermediate, calcium, metal-binding, thiamine pyrophosphate, transferase |
Biological source | Escherichia coli K12 |
Total number of polymer chains | 2 |
Total formula weight | 148252.68 |
Authors | Wille, G.,Asztalos, P.,Weiss, M.S.,Tittmann, K. (deposition date: 2007-09-11, release date: 2007-12-11, Last modification date: 2024-02-21) |
Primary citation | Asztalos, P.,Parthier, C.,Golbik, R.,Kleinschmidt, M.,Hubner, G.,Weiss, M.S.,Friedemann, R.,Wille, G.,Tittmann, K. Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate. Biochemistry, 46:12037-12052, 2007 Cited by PubMed: 17914867DOI: 10.1021/bi700844m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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