2R5N

Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transketolase 1	polymer	669	73121.5	2	UniProt (P27302) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Escherichia coli	TK 1
2	C (A)	RIBOSE-5-PHOSPHATE	non-polymer		230.1	1	Chemie (R5P) PubChem (230) PubChem (44588263) PubChem (77982) PubChem (53393537) PubChem (188324) PubChem (441187) PubChem (88507863) PubChem (88508108) PubChem (85049) PubChem (6101623) PubChem (14029334) PubChem (135075808)
3	D, N (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
4	E, P (A, B)	THIAMINE DIPHOSPHATE	non-polymer		425.3	2	Chemie (TPP) PubChem (1132)
5	F, G, H, I, J... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	16	Chemie (EDO)
6	O, Y (B)	5-O-phosphono-beta-D-ribofuranose	non-polymer		230.1	2	Chemie (RP5) PubChem (23422546) PubChem (24802507) PubChem (46876838) PubChem (53477706) PubChem (439167) PubChem (440101) PubChem (447568) PubChem (447634) PubChem (448203) PubChem (4175041) PubChem (91746440) PubChem (11401949) PubChem (118070650) PubChem (124350436) PubChem (13990819) PubChem (168368775) PubChem (172642146) PubChem (167077165) PubChem (168366045) PubChem (172641724)
7	AA, Z (B, A)	water	water		18.0	1628	Chemie (HOH)

Sequence modifications

A, B: 1 - 663 (UniProt: P27302)

PDB	External Database	Details
His 664	-	expression tag
His 665	-	expression tag
His 666	-	expression tag
His 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	146243.0
Non-Polymers*	Number of molecules	23
	Total formula weight	2614.2
All*	Total formula weight	148857.2

*Water molecules are not included.