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2P55
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X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP
分子名称: 2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ...
著者Ohren, J.F, Pavlovsky, A.G.
登録日2007-03-14
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase.
J.Med.Chem., 50, 2007
2P56
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Crystal structure of alpha-2,3-sialyltransferase from Campylobacter jejuni in apo form
分子名称: 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase
著者Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.
登録日2007-03-14
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
2P57
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GAP domain of ZNF289, an ID1-regulated zinc finger protein
分子名称: GTPase-activating protein ZNF289, UNKNOWN ATOM OR ION, ZINC ION
著者Tong, Y, Dimov, S, Shen, L, Zhu, H, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-03-14
公開日2007-03-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献GAP domain of ZNF289, an ID1-regulated zinc finger protein
To be Published
2P58
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Structure of the Yersinia pestis Type III secretion system needle protein YscF in complex with its chaperones YscE/YscG
分子名称: Putative type III secretion protein YscE, Putative type III secretion protein YscF, Putative type III secretion protein YscG
著者Sun, P, Austin, B.P, Tropea, J.E, Waugh, D.S.
登録日2007-03-14
公開日2008-03-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG.
J.Mol.Biol., 377, 2008
2P59
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Crystal Structure of Hepatitis C Virus NS3.4A protease
分子名称: (2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE, NS3, peptide
著者Perni, R.B, Wei, Y.
登録日2007-03-14
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Bioorg.Med.Chem.Lett., 17, 2007
2P5B
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BU of 2p5b by Molmil
The complex structure of JMJD2A and trimethylated H3K36 peptide
分子名称: FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ...
著者Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y.
登録日2007-03-14
公開日2007-06-12
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2P5C
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BU of 2p5c by Molmil
Crystal structure of PH0725 from Pyrococcus horikoshii OT3
分子名称: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase
著者Yamamoto, H, Taketa, M, Ono, N, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-15
公開日2007-09-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
2P5D
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Crystal structure of MJECL36 from Methanocaldococcus jannaschii DSM 2661
分子名称: UPF0310 protein MJECL36
著者Sugahara, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-15
公開日2007-09-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of MJECL36 from Methanocaldococcus jannaschii DSM 2661
To be Published
2P5E
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Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-15
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2P5F
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Crystal structure of PH0725 from Pyrococcus horikoshii OT3
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase
著者Sugahara, M, Yamamoto, H, Kageyama, Y, Taketa, M, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-15
公開日2007-09-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
2P5G
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BU of 2p5g by Molmil
Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template
分子名称: DNA polymerase, Primer DNA, Template DNA
著者Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
登録日2007-03-15
公開日2007-10-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2P5H
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BU of 2p5h by Molmil
sPLA2 inhibitor 9
分子名称: pip9
著者Thwin, M.M, Satyanarayanajois, D.S, Nagarajarao, L.M, Sato, K, Gopalakrishnakone, P.P, Arjunan, P.
登録日2007-03-15
公開日2007-11-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Novel Peptide Inhibitors of Human Secretory Phospholipase A2 with Antiinflammatory Activity: Solution Structure and Molecular Modeling.
J.Med.Chem., 50, 2007
2P5I
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Crystal structure of protein BH3822 from Bacillus halodurans, a member of the biotin/lipoate A/B protein ligase family
分子名称: BH3822 protein
著者Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-15
公開日2007-03-27
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of a hypothetical protein from Bacillus halodurans: Pfam-PF03099
To be Published
2P5J
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sPLA2 inhibitor pip 17
分子名称: pip17
著者Thwin, M.M, Satyanarayanajois, D.S, Nagarajarao, L.M, Sato, K, Gopalakrishnakone, P.P, Arjunan, P.
登録日2007-03-15
公開日2007-11-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Novel Peptide Inhibitors of Human Secretory Phospholipase A2 with Antiinflammatory Activity: Solution Structure and Molecular Modeling.
J.Med.Chem., 50, 2007
2P5K
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Crystal structure of the N-terminal domain of AhrC
分子名称: Arginine repressor
著者Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
登録日2007-03-15
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献A high-resolution structure of the DNA-binding domain of AhrC, the arginine repressor/activator protein from Bacillus subtilis.
Acta Crystallogr.,Sect.F, 63, 2007
2P5L
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BU of 2p5l by Molmil
Crystal structure of a dimer of N-terminal domains of AhrC in complex with an 18bp DNA operator site
分子名称: Arginine repressor, DNA (5'-D(*DCP*DAP*DTP*DGP*DAP*DAP*DTP*DAP*DAP*DAP*DAP*DAP*DTP*DTP*DCP*DAP*DAP*DG)-3'), DNA (5'-D(*DCP*DTP*DTP*DGP*DAP*DAP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DG)-3'), ...
著者Garnett, J.A, Marincs, F, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
登録日2007-03-15
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and function of the arginine repressor-operator complex from Bacillus subtilis.
J.Mol.Biol., 379, 2008
2P5M
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C-terminal domain hexamer of AhrC bound with L-arginine
分子名称: ARGININE, Arginine repressor
著者Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
登録日2007-03-15
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine.
Acta Crystallogr.,Sect.F, 63, 2007
2P5N
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Crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase in complex with coenzyme NADPH
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Aldo-keto reductase family 1, member C21, ...
著者El-Kabbani, O, Dhagat, U.
登録日2007-03-15
公開日2007-10-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme.
Acta Crystallogr.,Sect.F, 63, 2007
2P5O
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Crystal structure of RB69 GP43 in complex with DNA containing an abasic site analog
分子名称: DNA polymerase, Primer DNA, Template DNA
著者Hogg, M, Wallace, S.S, Doublie, S.
登録日2007-03-15
公開日2007-04-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site.
Embo J., 23, 2004
2P5P
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Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
分子名称: Genome polyprotein
著者Gao, F, Yuan, F, Gao, G.F.
登録日2007-03-16
公開日2008-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
To be Published
2P5Q
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Crystal structure of the poplar glutathione peroxidase 5 in the reduced form
分子名称: ACETATE ION, CADMIUM ION, Glutathione peroxidase 5
著者Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
登録日2007-03-16
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
2P5R
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Crystal structure of the poplar glutathione peroxidase 5 in the oxidized form
分子名称: CALCIUM ION, Glutathione peroxidase 5
著者Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
登録日2007-03-16
公開日2007-07-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
2P5S
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RAB domain of human RASEF in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, RAS and EF-hand domain containing, UNKNOWN ATOM OR ION
著者Zhu, H, Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-03-16
公開日2007-03-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献RAB domain of human RASEF in complex with GDP
To be Published
2P5T
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Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae
分子名称: PezT, Putative transcriptional regulator PezA, fragment of PezA helix-turn-helix motif
著者Loll, B, Meinhart, A.
登録日2007-03-16
公開日2007-05-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular and Structural Characterization of the PezAT Chromosomal Toxin-Antitoxin System of the Human Pathogen Streptococcus pneumoniae.
J.Biol.Chem., 282, 2007
2P5U
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Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
著者Fu, Z.-Q, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Dillard, B, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-16
公開日2007-04-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published

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