PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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2FZA	Crystal structure of d(GCGGGAGC): the base-intercalated duplex 分子名称: 5'-D(*GP*(CBR)P*GP*GP*GP*AP*GP*C)-3', CALCIUM ION, SODIUM ION 著者 Kondo, J, Ciengshin, T, Juan, E.C.M, Mitomi, K, Takenaka, A. 登録日 2006-02-09 公開日 2007-01-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Crystal structure of d(gcGXGAgc) with X=G: a mutation at X is possible to occur in a base-intercalated duplex for multiplex formation Nucleosides Nucleotides Nucleic Acids, 25, 2006
4UV0	Structure of a semisynthetic phosphorylated DAPK 分子名称: DEATH-ASSOCIATED PROTEIN KINASE 1, TRIETHYLENE GLYCOL 著者 de Diego, I, Rios, P, Meyer, C, Koehn, M, Wilmanns, M. 登録日 2014-08-01 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Molecular Mechanisms Behind Dapk Regulation: How the Phosphorylation Activity Switch Works To be Published
4UVR	Binding mode, selectivity and potency of N-indolyl-oxopyridinyl-4- amino-propanyl-based inhibitors targeting Trypanosoma cruzi CYP51 分子名称: Nalpha-{4-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-fluorobenzoyl}-N-pyridin-4-yl-D-tryptophanamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-DEMETHYLASE, ... 著者 Vieira, D.F, Choi, J.Y, Calvet, C.M, Gut, J, Kellar, D, Siqueira-Neto, J.L, Johnston, J.B, McKerrow, J.H, Roush, W.R, Podust, L.M. 登録日 2014-08-08 公開日 2014-11-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Binding Mode and Potency of N-Indolyl-Oxopyridinyl-4-Amino-Propanyl-Based Inhibitors Targeting Trypanosoma Cruzi Cyp51 J.Med.Chem., 57, 2014
6QL3	Crystal structure of chimeric carbonic anhydrase VI with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide 分子名称: 1,2-ETHANEDIOL, 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, BENZOIC ACID, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2019-01-31 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors. Sci Rep, 9, 2019
4UXN	LSD1(KDM1A)-CoREST in complex with Z-Pro derivative of MC2580 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, ... 著者 Rodriguez, V, Valente, S, Stazi, G, Lucidi, A, Mercurio, C, Vianello, P, Ciossani, G, Mattevi, A, Botrugno, O.A, Dessanti, P, Minucci, S, Varasi, M, Mai, A. 登録日 2014-08-27 公開日 2015-02-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells Chemmedchem, 6, 2015
2FXS	Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide 分子名称: ATP-dependent molecular chaperone HSP82, GLYCEROL, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-06 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design. J.Mol.Biol., 388, 2009
2FY6	Structure of the N-terminal domain of Neisseria meningitidis PilB 分子名称: CHLORIDE ION, Peptide methionine sulfoxide reductase msrA/msrB, SULFATE ION 著者 Ranaivoson, F.M, Kauffmann, B, Neiers, F, Boschi-Muller, S, Branlant, G, Favier, F. 登録日 2006-02-07 公開日 2006-04-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold J.Mol.Biol., 358, 2006
4V19	Structure of the large subunit of the mammalian mitoribosome, part 1 of 2 分子名称: MAGNESIUM ION, MITORIBOSOMAL 16S RRNA, MITORIBOSOMAL CP TRNA, ... 著者 Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N. 登録日 2014-09-25 公開日 2014-10-08 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome Nature, 515, 2014
6DAM	Crystal structure of lanthanide-dependent methanol dehydrogenase XoxF from Methylomicrobium buryatense 5G 分子名称: LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF, PYRROLOQUINOLINE QUINONE, ... 著者 Deng, Y, Ro, S.Y, Rosenzweig, A.C. 登録日 2018-05-01 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure and function of the lanthanide-dependent methanol dehydrogenase XoxF from the methanotroph Methylomicrobium buryatense 5GB1C. J. Biol. Inorg. Chem., 23, 2018
6DBD	Crystal Structure of VHH R326 分子名称: ACETATE ION, SODIUM ION, nanobody VHH R326 著者 Brooks, C.L, Toride King, M, Huh, I. 登録日 2018-05-03 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes. J. Biol. Chem., 293, 2018
4V7B	Visualization of two tRNAs trapped in transit during EF-G-mediated translocation 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Ramrath, D.J.F, Lancaster, L, Sprink, T, Mielke, T, Loerke, J, Noller, H.F, Spahn, C.M.T. 登録日 2013-10-27 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proc.Natl.Acad.Sci.USA, 110, 2013
7LZE	Cryo-EM Structure of disulfide stabilized HMPV F v4-B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Gorman, J, Kwong, P.D. 登録日 2021-03-09 公開日 2021-08-25 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses. Proc.Natl.Acad.Sci.USA, 118, 2021
4V7A	E. coli 70S-fMetVal-tRNAVal post-translocation complex (post4) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V7X	Structure of the Thermus thermophilus ribosome complexed with erythromycin. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. 登録日 2010-08-17 公開日 2014-07-09 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
2G0J	Crystal structure of SMU.848 from Streptococcus mutans 分子名称: hypothetical protein SMU.848 著者 Hou, H.-F, Gao, Z.-Q, Li, L.-F, Liang, Y.-H, Su, X.-D, Dong, Y.-H. 登録日 2006-02-13 公開日 2006-08-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of SMU.848 from Streptococcus mutans To be Published
6DDR	Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody 分子名称: Anti-MICA Fab fragment heavy chain clone 13A9, Anti-MICA Fab fragment light chain clone 13A9, GLYCEROL, ... 著者 Matsumoto, M.L. 登録日 2018-05-10 公開日 2018-10-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11, 2019
6D4A	Cell Surface Receptor with Bound Ligand at 1.75-A Resolution 分子名称: 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, GLYCEROL, Myeloid cell surface antigen CD33 著者 Hermans, S.J, Miles, L.A, Parker, M.W. 登録日 2018-04-17 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis. Iscience, 19, 2019
4UQI	AP2 controls clathrin polymerization with a membrane-activated switch 分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... 著者 Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. 登録日 2014-06-23 公開日 2014-07-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch. Science, 345, 2014
4UQX	Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, HSIE1 著者 Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. 登録日 2014-06-25 公開日 2014-10-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes. J.Biol.Chem., 289, 2014
4UTS	Room temperature crystal structure of the fast switching M159T mutant of fluorescent protein Dronpa 分子名称: FLUORESCENT PROTEIN DRONPA 著者 Kaucikas, M, Fitzpatrick, A, Bryan, E, Struve, A, Henning, R, Kosheleva, I, Srajer, V, van Thor, J.J. 登録日 2014-07-22 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Room Temperature Crystal Structure of the Fast Switching M159T Mutant of the Fluorescent Protein Dronpa. Proteins, 83, 2015
6ZGF	Spike Protein of RaTG13 Bat Coronavirus in Closed Conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wrobel, A.G, Benton, D.J, Rosenthal, P.B, Gamblin, S.J. 登録日 2020-06-18 公開日 2020-07-01 最終更新日 2020-09-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects. Nat.Struct.Mol.Biol., 27, 2020
4UX9	Crystal structure of JNK1 bound to a MKK7 docking motif 分子名称: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7, MITOGEN-ACTIVATED PROTEIN KINASE 8, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Kragelj, J, Palencia, A, Nanao, M.H, Maurin, D, Bouvignies, G, Blackledge, M, Ringkjobing-Jensen, M. 登録日 2014-08-20 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structure and Dynamics of the Mkk7-Jnk Signaling Complex. Proc.Natl.Acad.Sci.USA, 112, 2015
2FPG	Crystal structure of pig GTP-specific succinyl-CoA synthetase in complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, POTASSIUM ION, ... 著者 Fraser, M.E. 登録日 2006-01-16 公開日 2006-02-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Interactions of GTP with the ATP-grasp Domain of GTP-specific Succinyl-CoA Synthetase J.Biol.Chem., 281, 2006
4V1M	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
6D8F	RsAgo Ternary Complex with Guide RNA and Target DNA Containing T-T Bulge Within the Seed Segment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*TP*TP*TP*AP*AP*C)-3'), ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018

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