6RH3
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![BU of 6rh3 by Molmil](/molmil-images/mine/6rh3) | Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | 登録日 | 2019-04-18 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation. Mol.Cell, 75, 2019
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4YFN
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![BU of 4yfn by Molmil](/molmil-images/mine/4yfn) | Escherichia coli RNA polymerase in complex with squaramide compound 14 (N-[3,4-dioxo-2-(4-{[4-(trifluoromethyl)benzyl]amino}piperidin-1-yl)cyclobut-1-en-1-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S. | 登録日 | 2015-02-25 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.817 Å) | 主引用文献 | X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein. J.Med.Chem., 58, 2015
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1UVJ
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![BU of 1uvj by Molmil](/molmil-images/mine/1uvj) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA | 分子名称: | 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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1UVN
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![BU of 1uvn by Molmil](/molmil-images/mine/1uvn) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex | 分子名称: | 5'-R(*UP*UP*UP*UP*CP*CP)-3', CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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1UVI
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![BU of 1uvi by Molmil](/molmil-images/mine/1uvi) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 6nt RNA | 分子名称: | 5'-R(*UP*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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5VT0
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![BU of 5vt0 by Molmil](/molmil-images/mine/5vt0) | |
1UVL
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![BU of 1uvl by Molmil](/molmil-images/mine/1uvl) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B | 分子名称: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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1UVM
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![BU of 1uvm by Molmil](/molmil-images/mine/1uvm) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A | 分子名称: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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4BBS
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![BU of 4bbs by Molmil](/molmil-images/mine/4bbs) | Structure of an initially transcribing RNA polymerase II-TFIIB complex | 分子名称: | 5'-D(*AP*GP*CP*GP*CP*AP*GP*TP*TP*GP*TP*GP*CP*TP *AP*TP*GP*AP*TP*AP*TP*TP*TP*TP*TP*AP*TP)-3', 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*CP*TP)-3', 5'-R(*AP*UP*AP*UP*CP*AP)-3', ... | 著者 | Sainsbury, S, Niesser, J, Cramer, P. | 登録日 | 2012-09-27 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex Nature, 493, 2013
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4BBR
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![BU of 4bbr by Molmil](/molmil-images/mine/4bbr) | Structure of RNA polymerase II-TFIIB complex | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Sainsbury, S, Niesser, J, Cramer, P. | 登録日 | 2012-09-27 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex Nature, 493, 2013
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1UVK
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![BU of 1uvk by Molmil](/molmil-images/mine/1uvk) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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7S01
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![BU of 7s01 by Molmil](/molmil-images/mine/7s01) | X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | 著者 | Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V. | 登録日 | 2021-08-28 | 公開日 | 2022-07-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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4BY7
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![BU of 4by7 by Molmil](/molmil-images/mine/4by7) | elongating RNA Polymerase II-Bye1 TLD complex | 分子名称: | , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-18 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4BXX
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![BU of 4bxx by Molmil](/molmil-images/mine/4bxx) | Arrested RNA polymerase II-Bye1 complex | 分子名称: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-16 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
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3UR0
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![BU of 3ur0 by Molmil](/molmil-images/mine/3ur0) | Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2011-11-21 | 公開日 | 2012-05-02 | 最終更新日 | 2012-05-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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3UPF
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![BU of 3upf by Molmil](/molmil-images/mine/3upf) | Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023 | 分子名称: | 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2011-11-18 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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7S00
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![BU of 7s00 by Molmil](/molmil-images/mine/7s00) | X-ray structure of the phage AR9 non-virion RNA polymerase core | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | 著者 | Leiman, P.G, Sokolova, M.L, Fraser, A. | 登録日 | 2021-08-28 | 公開日 | 2022-07-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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4BY1
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![BU of 4by1 by Molmil](/molmil-images/mine/4by1) | elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP | 分子名称: | 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | 登録日 | 2013-07-17 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
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2JA5
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![BU of 2ja5 by Molmil](/molmil-images/mine/2ja5) | CPD lesion containing RNA Polymerase II elongation complex A | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TTP*TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | 登録日 | 2006-11-23 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Cpd Damage Recognition by Transcribing RNA Polymerase II Science, 315, 2007
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8SY5
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![BU of 8sy5 by Molmil](/molmil-images/mine/8sy5) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site | 分子名称: | 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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8SY6
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![BU of 8sy6 by Molmil](/molmil-images/mine/8sy6) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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8SY7
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![BU of 8sy7 by Molmil](/molmil-images/mine/8sy7) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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1KHW
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![BU of 1khw by Molmil](/molmil-images/mine/1khw) | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | 登録日 | 2001-12-01 | 公開日 | 2002-01-16 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
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6VJS
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![BU of 6vjs by Molmil](/molmil-images/mine/6vjs) | |
1KHV
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![BU of 1khv by Molmil](/molmil-images/mine/1khv) | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ | 分子名称: | LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | 登録日 | 2001-12-01 | 公開日 | 2002-01-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
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