3UR0

Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin

Summary for 3UR0

Entry DOI	10.2210/pdb3ur0/pdb
Related	3NAH 3NAI 3UPF 3UQS
Descriptor	RNA-dependent RNA polymerase, SULFATE ION, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, ... (4 entities in total)
Functional Keywords	rna-dependent rna polymerase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	murine norovirus
Total number of polymer chains	3
Total formula weight	179870.55
Authors	Milani, M.,Mastrangelo, E.,Bolognesi, M. (deposition date: 2011-11-21, release date: 2012-05-02, Last modification date: 2012-05-23)
Primary citation	Mastrangelo, E.,Pezzullo, M.,Tarantino, D.,Petazzi, R.,Germani, F.,Kramer, D.,Robel, I.,Rohayem, J.,Bolognesi, M.,Milani, M. Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419:198-210, 2012 Cited by PubMed: 22446684 DOI: 10.1016/j.jmb.2012.03.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation