2JA5

CPD lesion containing RNA Polymerase II elongation complex A

Summary for 2JA5

Related1I3Q 1I50 1I6H 1K83 1NIK 1NT9 1PQV 1R5U 1R9S 1R9T 1SFO 1TWA 1TWC 1TWF 1TWG 1TWH 1WCM 1Y1V 1Y1W 1Y1Y 1Y77 2B63 2B8K 1DZF 1A1D 1Y14 2JA6 2JA7 2JA8
DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (16 entities in total)
Functional Keywordsdna-directed rna polymerase, lesion recognition, transferase/dna/rna, dna damage, zinc-finger, dna-binding, photolesion, phosphorylation, misincorporation, rna polymerase ii, transcription- coupled repair, cyclobutane pyrimidine dimer, tcr, cpd, zinc, arrest, stalling, dna lesion, metal-binding, nuclear protein, transcription bubble, nucleotidyltransferase, damage recognition, elongation complex, transferase, thymine dimer, transcription
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
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Cellular locationNucleus P04050 P08518 P16370 P20433 P20434 P34087 P20436 P38902
Cytoplasm  P20435
Nucleus, nucleolus  P27999 P22139 P40422
Total number of polymer chains14
Total molecular weight526145.98
Authors
Brueckner, F.,Hennecke, U.,Carell, T.,Cramer, P. (deposition date: 2006-11-23, release date: 2007-02-20, Last modification date: 2017-03-29)
Primary citation
Brueckner, F.,Hennecke, U.,Carell, T.,Cramer, P.
Cpd Damage Recognition by Transcribing RNA Polymerase II
Science, 315:859-, 2007
PubMed: 17290000 (PDB entries with the same primary citation)
DOI: 10.1126/SCIENCE.1135400
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2375210.3%8.8%1.0%0.53MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report