1K83

Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin

Summary for 1K83

Related1I50 2VUM 3CQZ
Related PRD IDPRD_000201
DescriptorDNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, DNA-DIRECTED RNA POLYMERASE II 140KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 45KD POLYPEPTIDE, ... (14 entities in total)
Functional Keywordstranscription-toxin complex, alpha amanitin, toxin, inhibitor, polymerase, transferase, dna binding, zinc-finger, phosphoprotein, transcription, ubl transcription-toxin complex, transcription/toxin
Biological sourceSACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
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Cellular locationNucleus P04050 P08518 P16370 P20434 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains11
Total molecular weight471143.19
Authors
Bushnell, D.A.,Cramer, P.,Kornberg, R.D. (deposition date: 2001-10-22, release date: 2002-02-13, Last modification date: 2012-12-12)
Primary citation
Bushnell, D.A.,Cramer, P.,Kornberg, R.D.
Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
Proc.Natl.Acad.Sci.USA, 99:1218-, 2002
PubMed: 11805306 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.251664698
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.277333.7%5.6%5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report