12-subunit RNA Polymerase II

Summary for 2B8K

DescriptorDNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ... (13 entities in total)
Functional Keywordsdna-directed rna polymerase, dna-dependent rna polymerase, cellular rna polymerase, metal-binding, nuclear protein, transcription, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationNucleus P04050 P08518 P16370 P20433 P20434 P34087 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains12
Total molecular weight519749.21
Meyer, P.A.,Ye, P.,Zhang, M.,Suh, M.H.,Fu, J. (deposition date: 2005-10-07, release date: 2006-06-20, Last modification date: 2012-06-13)
Primary citation
Meyer, P.A.,Ye, P.,Zhang, M.,Suh, M.H.,Fu, J.
Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14:973-982, 2006
PubMed: 16765890 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2006.04.003
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers4911.2%8.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2b8k
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Molmil generated image of 2b8k
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Molmil generated image of 2b8k
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