2B8K
12-subunit RNA Polymerase II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase II largest subunit | polymer | 1733 | 191821.6 | 1 | UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Saccharomyces cerevisiae (baker's yeast) | RNA polymerase II subunit 1, B220 |
| 2 | B (B) | DNA-directed RNA polymerase II 140 kDa polypeptide | polymer | 1224 | 138937.3 | 1 | UniProt (P08518) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Saccharomyces cerevisiae (baker's yeast) | B150, RNA polymerase II subunit 2 |
| 3 | C (C) | DNA-directed RNA polymerase II 45 kDa polypeptide | polymer | 318 | 35330.5 | 1 | UniProt (P16370) Pfam (PF01193) Pfam (PF01000) | Saccharomyces cerevisiae (baker's yeast) | B44.5 |
| 4 | D (D) | DNA-directed RNA polymerase II 32 kDa polypeptide | polymer | 221 | 25451.2 | 1 | UniProt (P20433) Pfam (PF03874) | Saccharomyces cerevisiae (baker's yeast) | B32 |
| 5 | E (E) | DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide | polymer | 215 | 25117.1 | 1 | UniProt (P20434) Pfam (PF03871) Pfam (PF01191) | Saccharomyces cerevisiae (baker's yeast) | ABC27 |
| 6 | F (F) | DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) | Saccharomyces cerevisiae (baker's yeast) | ABC23 |
| 7 | G (G) | DNA-directed RNA polymerase II 19 kDa polypeptide | polymer | 215 | 24148.8 | 1 | UniProt (P34087) Pfam (PF03876) Pfam (PF00575) | Saccharomyces cerevisiae (baker's yeast) | B16 |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide | polymer | 146 | 16525.4 | 1 | UniProt (P20436) Pfam (PF03870) | Saccharomyces cerevisiae (baker's yeast) | ABC14.4 |
| 9 | I (I) | DNA-directed RNA polymerase II subunit 9 | polymer | 122 | 14308.2 | 1 | UniProt (P27999) Pfam (PF02150) Pfam (PF01096) | Saccharomyces cerevisiae (baker's yeast) | DNA-directed RNA polymerase II 14.2 kDa polypeptide, B12.6 |
| 10 | J (J) | DNA-directed RNA polymerases I/II/III subunit 10 | polymer | 70 | 8290.7 | 1 | UniProt (P22139) Pfam (PF01194) | Saccharomyces cerevisiae (baker's yeast) | DNA- directed RNA polymerases I, II, and III 8.3 kDa polypeptide, ABC10- beta, ABC8 |
| 11 | K (K) | DNA-directed RNA polymerase II 13.6 kDa polypeptide | polymer | 120 | 13633.5 | 1 | UniProt (P38902) Pfam (PF13656) | Saccharomyces cerevisiae (baker's yeast) | B13.6 |
| 12 | L (L) | DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide | polymer | 70 | 7730.0 | 1 | UniProt (P40422) Pfam (PF03604) | Saccharomyces cerevisiae (baker's yeast) | ABC10-alpha |
| 13 | M, N, O, P, Q... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
G: 1 - 171 (UniProt: P34087)
| PDB | External Database | Details |
|---|---|---|
| Ser 172 | - | expression tag |
| His 173 | - | expression tag |
| Glu 174 | - | expression tag |
| Lys 175 | - | expression tag |
| Arg 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Trp 178 | - | expression tag |
| Lys 179 | - | expression tag |
| Lys 180 | - | expression tag |
| Asn 181 | - | expression tag |
| Phe 182 | - | expression tag |
| Ile 183 | - | expression tag |
| Ala 184 | - | expression tag |
| Val 185 | - | expression tag |
| Ser 186 | - | expression tag |
| Ala 187 | - | expression tag |
| Ala 188 | - | expression tag |
| Asn 189 | - | expression tag |
| Arg 190 | - | expression tag |
| Phe 191 | - | expression tag |
| Lys 192 | - | expression tag |
| Lys 193 | - | expression tag |
| Ile 194 | - | expression tag |
| Ser 195 | - | expression tag |
| Ser 196 | - | expression tag |
| Ser 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Ala 199 | - | expression tag |
| Leu 200 | - | expression tag |
| Asp 201 | - | expression tag |
| Tyr 202 | - | expression tag |
| Asp 203 | - | expression tag |
| Ile 204 | - | expression tag |
| Pro 205 | - | expression tag |
| Thr 206 | - | expression tag |
| Thr 207 | - | expression tag |
| Ala 208 | - | expression tag |
| Ser 209 | - | expression tag |
| Glu 210 | - | expression tag |
| Asn 211 | - | expression tag |
| Leu 212 | - | expression tag |
| Tyr 213 | - | expression tag |
| Phe 214 | - | expression tag |
| Gln 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 519225.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 523.3 | |
| All* | Total formula weight | 519749.2 |
