1Y77

Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP

Summary for 1Y77

Related1Y1W
Descriptor5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... (18 entities in total)
Functional Keywordstranscription, substrate, ntp, elongation, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid
Biological sourceSaccharomyces cerevisiae (baker's yeast)
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Cellular locationNucleus P04050 P08518 P16370 P20433 P20434 P34087 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains15
Total molecular weight526383.23
Authors
Kettenberger, H.,Armache, K.-J.,Cramer, P. (deposition date: 2004-12-08, release date: 2005-01-04, Last modification date: 2012-04-18)
Primary citation
Kettenberger, H.,Armache, K.-J.,Cramer, P.
Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16:955-965, 2004
PubMed: 15610738 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2004.11.040
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (4.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone4911.4%8.6%0.2%0.36MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report