RNA polymerase II complexed with ATP

Summary for 1TWA

Related1twc 1twf 1twg 1twh
DescriptorDNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ... (13 entities in total)
Functional Keywordstranscription, mrna, multiprotein complex, molecular machine, zinc motifs
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationNucleus P04050 P08518 P16370 P20434 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains10
Total molecular weight470766.31
Westover, K.D.,Bushnell, D.A.,Kornberg, R.D. (deposition date: 2004-06-30, release date: 2004-11-16, Last modification date: 2011-07-13)
Primary citation
Westover, K.D.,Bushnell, D.A.,Kornberg, R.D.
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119:481-489, 2004
PubMed: 15537538 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2004.10.016
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23833 4.6% 17.5% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21