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1PLQ
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
分子名称: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
著者Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
登録日1995-01-02
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
1C8M
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REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS
分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION
著者Chakravarty, S, Bator, C.M, Pevear, D.C, Diana, G.D, Rossmann, M.G.
登録日2000-05-26
公開日2000-11-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献THE REFINED STRUCTURE OF A PICORNAVIRUS INHIBITOR CURRENTLY IN CLINICAL TRIALS, WHEN COMPLEXED WITH HUMAN RHINOVIRUS 16
to be published
6YI9
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Crystal structure of the rat cytosolic PCK1, acetylated on Lys244
分子名称: 1,2-ETHANEDIOL, Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
著者Latorre-Muro, P, Baeza, J, Hurtado-Guerrero, R, Hicks, T, Delso, I, Hernandez-Ruiz, C, Velazquez-Campoy, A, Lawton, A.J, Angulo, J, Denu, J.M, Carrodeguas, J.A.
登録日2020-04-01
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity.
J.Biol.Chem., 296, 2021
4LG0
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Structure of a ternary FOXO1-ETS1 DNA complex
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DAP*DAP*DCP*DAP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DAP*DAP*DAP*DCP*DCP*DGP*DTP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3'), ...
著者Birrane, G, Choy, W.C, Datta, D, Geiger, C.A, Grant, M.A.
登録日2013-06-27
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structure of a ternary FOXO1-ETS1 DNA complex
To be Published
5I9E
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BU of 5i9e by Molmil
Crystal structure of a nuclear actin ternary complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
著者Chen, Z, Cao, T.
登録日2016-02-20
公開日2016-07-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a nuclear actin ternary complex.
Proc.Natl.Acad.Sci.USA, 113, 2016
6S1C
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BU of 6s1c by Molmil
P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex
分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ...
著者Grabarczyk, D.B.
登録日2019-06-18
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6.1 Å)
主引用文献Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.
Nucleic Acids Res., 48, 2020
8OQI
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Cryo-EM structure of the wild-type alpha-synuclein fibril.
分子名称: Alpha-synuclein
著者Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G.
登録日2023-04-12
公開日2024-03-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease.
Brain, 147, 2024
4PJT
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Structure of PARP1 catalytic domain bound to inhibitor BMN 673
分子名称: (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one, GLYCEROL, Poly [ADP-ribose] polymerase 1, ...
著者Aoyagi-Scharber, M, Gardberg, A.S, Arakaki, T.L.
登録日2014-05-12
公開日2014-09-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone.
Acta Crystallogr.,Sect.F, 70, 2014
3ODE
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BU of 3ode by Molmil
Human PARP-1 zinc finger 2 (Zn2) bound to DNA
分子名称: 5'-D(*CP*CP*CP*AP*AP*GP*CP*G)-3', 5'-D(*CP*GP*CP*TP*TP*GP*GP*G)-3', Poly [ADP-ribose] polymerase 1, ...
著者Pascal, J.M, Langelier, M.-F.
登録日2010-08-11
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
3ODC
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Human PARP-1 zinc finger 2 (Zn2) bound to DNA
分子名称: 5'-D(*CP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*G)-3', Poly [ADP-ribose] polymerase 1, ...
著者Pascal, J.M, Langelier, M.-F.
登録日2010-08-11
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
3B8P
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BU of 3b8p by Molmil
Fragment of WzzB, Polysaccharide Co-polymerase from Salmonella Typhimurium
分子名称: Chain length determinant protein
著者Tocilj, A, Matte, A, Cygler, M.
登録日2007-11-01
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Nat.Struct.Mol.Biol., 15, 2008
3B8M
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Structure of FepE- Bacterial Polysaccharide Co-polymerase
分子名称: Ferric enterobactin (Enterochelin) transport
著者Tocilj, A, Matte, A, Cygler, M.
登録日2007-11-01
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Nat.Struct.Mol.Biol., 15, 2008
3B8O
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BU of 3b8o by Molmil
Structure of WzzE- Bacterial Polysaccharide Co-polymerase
分子名称: Lipopolysaccharide biosynthesis protein wzzE
著者Tocilj, A, Matte, A, Cygler, M.
登録日2007-11-01
公開日2008-01-22
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Nat.Struct.Mol.Biol., 15, 2008
7YXP
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BU of 7yxp by Molmil
Crystal structure of WT AncGR2-LBD WT bound to dexamethasone and SHP coregulator fragment
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-16
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
7YXD
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BU of 7yxd by Molmil
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, SHP NR Box 1 Peptide, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-15
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
7YXC
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Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, CARBONATE ION, DEXAMETHASONE, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-15
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
7YXO
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BU of 7yxo by Molmil
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-16
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
7YXR
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Crystal structure of mutant AncGR2-LBD (Y545A) bound to dexamethasone and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, FORMIC ACID, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-16
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
7YXN
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BU of 7yxn by Molmil
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, DEXAMETHASONE, FORMIC ACID, ...
著者Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
登録日2022-02-16
公開日2022-12-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res., 50, 2022
3B8N
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Structure of FepE- Bacterial Polysaccharide Co-polymerase
分子名称: Ferric enterobactin (Enterochelin) transport
著者Tocilj, A, Matte, A, Cygler, M.
登録日2007-11-01
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Nat.Struct.Mol.Biol., 15, 2008
8I6V
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BU of 8i6v by Molmil
Cryo-EM structure of the polyphosphate polymerase VTC complex(Vtc4/Vtc3/Vtc1)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Mayer, A, Wu, S, Ye, S.
登録日2023-01-29
公開日2023-03-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Cryo-EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit.
Embo J., 42, 2023
1HRV
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HRV14/SDZ 35-682 COMPLEX
分子名称: 1-[2-HYDROXY-3-(4-CYCLOHEXYL-PHENOXY)-PROPYL]-4-(2-PYRIDYL)-PIPERAZINE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Oren, D.A, Zhang, A, Arnold, E.
登録日1995-03-02
公開日1995-06-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献SDZ 35-682, a new picornavirus capsid-binding agent with potent antiviral activity.
Antiviral Res., 26, 1995
4PH5
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BU of 4ph5 by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a AC at N-1 position and GC at N position
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Koag, M.C, Lee, S.
登録日2014-05-04
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
2V8O
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Structure of the Murray Valley encephalitis virus RNA helicase to 1. 9A resolution
分子名称: FLAVIVIRIN PROTEASE NS3
著者Mancini, E.J, Assenberg, R, Verma, A, Walter, T.S, Tuma, R, Grimes, J.M, Owens, R.J, Stuart, D.I.
登録日2007-08-09
公開日2007-08-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Murray Valley Encephalitis Virus RNA Helicase at 1.9 A Resolution.
Protein Sci., 16, 2007
3FS0
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Class II ligase ribozyme product-template duplex, structure 2
分子名称: 5'-R(*CP*CP*AP*GP*UP*CP*GP*GP*AP*AP*C)-3', 5'-R(*GP*GP*UP*GP*AP*GP*GP*CP*UP*G)-3', MAGNESIUM ION
著者Pitt, J.N, Ferre-D'Amare, A.R.
登録日2009-01-08
公開日2009-02-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-guided engineering of the regioselectivity of RNA ligase ribozymes.
J.Am.Chem.Soc., 131, 2009

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