4LG0

Structure of a ternary FOXO1-ETS1 DNA complex

Summary for 4LG0

Related3COA 3CO6 1K79 2STT
DescriptorForkhead box protein O1, Protein C-ets-1, DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3'), ... (7 entities in total)
Functional Keywordsdeoxyribonucleic acid, complex (dna-binding protein-dna), phosphoprotein, proto-oncogene, transcription-dna complex, winged helix, forkhead domain, ets binding domain, helix-turn-helix, transcription, transcription regulation, dna-binding, phosphorylation, nucleus, transcription/dna
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm Q12778 P14921
Total number of polymer chains4
Total molecular weight41080.37
Authors
Birrane, G.,Choy, W.C.,Datta, D.,Geiger, C.A.,Grant, M.A. (deposition date: 2013-06-27, release date: 2014-07-02)
Primary citation
Birrane, G.,Choy, W.C.,Datta, D.,Geiger, C.A.,Grant, M.A.
Structure of a ternary FOXO1-ETS1 DNA complex
To be Published,
Experimental method
X-RAY DIFFRACTION (2.19 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24061.6%1.7%6.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4lg0
no rotation
Molmil generated image of 4lg0
rotated about x axis by 90°
Molmil generated image of 4lg0
rotated about y axis by 90°