4LG0
Structure of a ternary FOXO1-ETS1 DNA complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Forkhead box protein O1 | polymer | 133 | 14788.6 | 1 | UniProt (Q12778) Pfam (PF00250) In PDB | Homo sapiens (human) | Forkhead box protein O1A, Forkhead in rhabdomyosarcoma |
2 | B | Protein C-ets-1 | polymer | 112 | 13174.1 | 1 | UniProt (P14921) Pfam (PF00178) In PDB | Homo sapiens (human) | p54 |
3 | C | DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3') | polymer | 21 | 6401.1 | 1 | |||
4 | D | DNA (5'-D(*DAP*DAP*DAP*DCP*DAP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DAP*DAP*DAP*DCP*DCP*DGP*DTP*DG)-3') | polymer | 21 | 6482.3 | 1 | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
6 | B | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
7 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 143 - 270 (UniProt: Q12778)
B: 331 - 440 (UniProt: P14921)
PDB | External Database | Details |
---|---|---|
Gly 138 | - | expression tag |
Pro 139 | - | expression tag |
Gly 140 | - | expression tag |
Tyr 141 | - | expression tag |
Pro 142 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 329 | - | expression tag |
Gly 330 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 40846.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 234.3 | |
All* | Total formula weight | 41080.4 |