PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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6WL0	Cryo-EM of Form 1 related peptide filament, 36-31-3-RD 分子名称: peptide 36-31-3-RD 著者 Wang, F, Gnewou, O.M, Su, Z, Egelman, E.H, Conticello, V.P. 登録日 2020-04-17 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
6WL8	Cryo-EM of Form 2 peptide filament 分子名称: Form 2 peptide 著者 Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. 登録日 2020-04-18 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
6W2Q	Junction 34, DHR53-DHR4 分子名称: CALCIUM ION, Junction 34 著者 Bick, M.J, Brunette, T.J, Baker, D. 登録日 2020-03-08 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Modular repeat protein sculpting using rigid helical junctions. Proc.Natl.Acad.Sci.USA, 117, 2020
1Z9W	Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis 分子名称: Dihydroneopterin aldolase 著者 Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2005-04-05 公開日 2005-04-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J.Mol.Biol., 349, 2005
6W1D	Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A resolution (NIAU)2 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2020-03-04 公開日 2020-03-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.795 Å) 主引用文献 The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
6W2W	Junction 24, DHR14-DHR18 分子名称: Junction 24 DHR14-DHR18 著者 Bick, M.J, Brunette, T.J, Baker, D. 登録日 2020-03-08 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Modular repeat protein sculpting using rigid helical junctions. Proc.Natl.Acad.Sci.USA, 117, 2020
3J6B	Structure of the yeast mitochondrial large ribosomal subunit 分子名称: 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... 著者 Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. 登録日 2014-01-22 公開日 2014-04-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the yeast mitochondrial large ribosomal subunit. Science, 343, 2014
6W2V	Junction 23, DHR14-DHR18 分子名称: Junction 23 DHR14-DHR18 著者 Bick, M.J, Brunette, T.J, Baker, D. 登録日 2020-03-08 公開日 2020-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Modular repeat protein sculpting using rigid helical junctions. Proc.Natl.Acad.Sci.USA, 117, 2020
6W6W	Cryo-EM structure of CST bound to telomeric single-stranded DNA 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 Lim, C, Barbour, A.T, Zaug, A.J, Goodrich, K.J, McKay, A.E, Wuttke, D.S, Cech, T.R. 登録日 2020-03-17 公開日 2020-06-03 最終更新日 2020-06-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science, 368, 2020
4GXH	Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 分子名称: CHLORIDE ION, PHOSPHATE ION, Pyrrolidone-carboxylate peptidase 著者 Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-09-04 公開日 2012-09-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 (CASP Target) To be Published
8BP0	Crystal structure of BHMeHis1.8, an engineered enzyme for the Morita-Baylis-Hillman reaction 分子名称: 1,2-ETHANEDIOL, BHMeHis1.8, TRIETHYLENE GLYCOL 著者 Hardy, F.J. 登録日 2022-11-15 公開日 2024-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.621 Å) 主引用文献 A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme. Nat Commun, 15, 2024
8BP1	Crystal structure of BHMeHis1.0, an engineered enzyme for the Morita-Baylis-Hillman reaction 分子名称: ACETATE ION, BHMeHis1.0, DI(HYDROXYETHYL)ETHER, ... 著者 Hardy, F.J. 登録日 2022-11-15 公開日 2024-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme. Nat Commun, 15, 2024
6WI2	Structure of human mitochondrial complex Nfs1-ISCU2-ISD11 with E.coli ACP1 at 1.95 A resolution (NIAU)2. N-terminal mutation of ISCU2 (L35) traps Nfs1 Cys loop in the active site of ISCU2 without metal present. 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2020-04-08 公開日 2020-04-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
3KW3	Crystal structure of alanine racemase from Bartonella henselae with covalently bound pyridoxal phosphate 分子名称: Alanine racemase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-11-30 公開日 2009-12-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011
4CIL	YopM-InlB: Hybrid leucine-rich repeat protein 分子名称: YOPM-CAP, INTERNALIN B 著者 Breitsprecher, D, Niemann, H.H. 登録日 2013-12-11 公開日 2014-04-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of an Engineered Yopm-Inlb Hybrid Protein. Bmc Struct.Biol., 14, 2014
6A42	R1EN(5-223)-ubiquitin fusion 分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C 著者 Maita, N. 登録日 2018-06-19 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
3VBW	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: 1,3-dioxo-2,3-dihydro-1H-indene-2-carbonitrile, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
6AI5	Disulfide-free, Zn-directed tetramer of the engineered cyt cb562 variant, C96T/A104AB3 分子名称: CHLORIDE ION, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Song, W.J, Tezcan, F.A. 登録日 2018-08-21 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Disulfide-free, Zn-directed tetramer of the engineered cyt cb562 variant, C96T/A104AB3 To Be Published
6AR9	Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic acid 分子名称: Hypoxanthine-guanine phosphoribosyltransferase, putative, MAGNESIUM ION, ... 著者 Teran, D, Gudday, L.W. 登録日 2017-08-21 公開日 2018-03-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery. PLoS Negl Trop Dis, 12, 2018
6ETI	Structure of inhibitor-bound ABCG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. 登録日 2017-10-26 公開日 2018-04-11 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
6EZM	Imidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiae 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid 著者 Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P. 登録日 2017-11-15 公開日 2018-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F8J	Crystal Structure of E. coli GyraseB 24kDa in complex with 6-[(ethylcarbamoyl)amino]-4-(1H-pyrazol-1-yl)-N-(pyridin-3-yl)pyridine-3-carboxamide 分子名称: 6-(ethylcarbamoylamino)-4-pyrazol-1-yl-~{N}-pyridin-3-yl-pyridine-3-carboxamide, DNA gyrase subunit B 著者 Narramore, S.K, Stevenson, C.E.M, Lawson, D.M, Maxwell, A, Fishwick, C.W.G. 登録日 2017-12-13 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase. Bioorg.Med.Chem., 27, 2019
6F96	Crystal Structure of E. coli GyraseB 24kDa in complex with 6-[(ethylcarbamoyl)amino]-4-[(4-methoxyphenyl)amino]-N-(pyridin-3-yl)pyridine-3-carboxamide 分子名称: 6-(ethylcarbamoylamino)-4-[(4-methoxyphenyl)amino]-~{N}-pyridin-3-yl-pyridine-3-carboxamide, DNA gyrase subunit B 著者 Narramore, S.K, Stevenson, C.E.M, Lawson, D.M, Maxwell, A, Fishwick, C.W.G. 登録日 2017-12-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase. Bioorg.Med.Chem., 27, 2019
3OGZ	Protein structure of USP from L. major in Apo-form 分子名称: GLYCEROL, UDP-sugar pyrophosphorylase 著者 Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. 登録日 2010-08-17 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
6EZJ	Imidazoleglycerol-phosphate dehydratase 分子名称: Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, ... 著者 Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P. 登録日 2017-11-15 公開日 2018-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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