6EZJ

Imidazoleglycerol-phosphate dehydratase

Summary for 6EZJ

Entry DOI	10.2210/pdb6ezj/pdb
EMDB information	3999
Descriptor	Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid (3 entities in total)
Functional Keywords	inhibitor, histidine biosynthesis, lyase, complex
Biological source	Arabidopsis thaliana (Thale cress)
Total number of polymer chains	24
Total formula weight	544995.05
Authors	Rawson, S.,Bisson, C.,Hurdiss, D.L.,Muench, S.P. (deposition date: 2017-11-15, release date: 2018-02-07, Last modification date: 2019-12-11)
Primary citation	Rawson, S.,Bisson, C.,Hurdiss, D.L.,Fazal, A.,McPhillie, M.J.,Sedelnikova, S.E.,Baker, P.J.,Rice, D.W.,Muench, S.P. Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115:1795-1800, 2018 Cited by PubMed: 29434040 DOI: 10.1073/pnas.1708839115 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation