4LG8
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![BU of 4lg8 by Molmil](/molmil-images/mine/4lg8) | Crystal structure of PRPF19 WD40 repeats | 分子名称: | Pre-mRNA-processing factor 19, SODIUM ION, UNKNOWN ATOM OR ION | 著者 | Xu, C, Tempel, W, He, H, Dobrovetsky, E, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-06-27 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal structure of the WD40 domain of human PRPF19. Biochem. Biophys. Res. Commun., 493, 2017
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2N7M
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![BU of 2n7m by Molmil](/molmil-images/mine/2n7m) | NMR-SAXS/WAXS Structure of the core of the U4/U6 di-snRNA | 分子名称: | RNA (92-MER) | 著者 | Cornilescu, G, Didychuk, A.L, Rodgers, M.L, Michael, L.A, Burke, J.E, Montemayor, E.J, Hoskins, A.A, Butcher, S.E, Tonelli, M. | 登録日 | 2015-09-14 | 公開日 | 2015-12-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA. J.Mol.Biol., 428, 2016
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1JMT
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![BU of 1jmt by Molmil](/molmil-images/mine/1jmt) | X-ray Structure of a Core U2AF65/U2AF35 Heterodimer | 分子名称: | HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT | 著者 | Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K. | 登録日 | 2001-07-19 | 公開日 | 2001-09-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. Cell(Cambridge,Mass.), 106, 2001
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6HYU
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![BU of 6hyu by Molmil](/molmil-images/mine/6hyu) | Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA | 分子名称: | 1,2-ETHANEDIOL, ATP-dependent RNA helicase DHX8, RNA (5'-R(*A*AP*A)-3'), ... | 著者 | Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476, 2019
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6HYS
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![BU of 6hys by Molmil](/molmil-images/mine/6hys) | Crystal structure of DHX8 helicase domain bound to ADP at 2.6 angstrom | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476, 2019
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1O6W
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6HYT
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![BU of 6hyt by Molmil](/molmil-images/mine/6hyt) | Crystal structure of DHX8 helicase domain bound to ADP at 2.3 Angstrom | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochem.J., 476, 2019
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4PEH
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![BU of 4peh by Molmil](/molmil-images/mine/4peh) | Dbr1 in complex with synthetic linear RNA | 分子名称: | GLYCEROL, MANGANESE (II) ION, RNA (5'-R(*CP*UP*AP*(A2P)P*AP*CP*AP*A)-3'), ... | 著者 | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | 登録日 | 2014-04-23 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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5G2Y
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![BU of 5g2y by Molmil](/molmil-images/mine/5g2y) | Structure a of Group II Intron Complexed with its Reverse Transcriptase | 分子名称: | GROUP II INTRON | 著者 | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | 登録日 | 2016-04-16 | 公開日 | 2016-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure of a Group II Intron in Complex with its Reverse Transcriptase. Nat.Struct.Mol.Biol., 23, 2016
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5G2X
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![BU of 5g2x by Molmil](/molmil-images/mine/5g2x) | Structure a of Group II Intron Complexed with its Reverse Transcriptase | 分子名称: | 5'-R(*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*CP)-3', GROUP II INTRON, GROUP II INTRON-ENCODED PROTEIN LTRA | 著者 | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | 登録日 | 2016-04-16 | 公開日 | 2016-05-11 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of a Group II Intron in Complex with its Reverse Transcriptase. Nat.Struct.Mol.Biol., 23, 2016
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | 分子名称: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | 著者 | Montemayor, E.J, Brow, D.A, Butcher, S.E. | 登録日 | 2016-09-24 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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2M0G
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![BU of 2m0g by Molmil](/molmil-images/mine/2m0g) | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition | 分子名称: | Splicing factor 1, Splicing factor U2AF 65 kDa subunit | 著者 | Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. | 登録日 | 2012-10-25 | 公開日 | 2013-01-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition. Nucleic Acids Res., 41, 2013
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2MY2
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6HIP
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![BU of 6hip by Molmil](/molmil-images/mine/6hip) | Structure of SPF45 UHM bound to HIV-1 Rev ULM | 分子名称: | HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... | 著者 | Pabis, M, Corsini, L, Sattler, M. | 登録日 | 2018-08-30 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
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6JUI
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![BU of 6jui by Molmil](/molmil-images/mine/6jui) | The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces | 分子名称: | Pre-mRNA-splicing factor CEF1 | 著者 | Wang, C, Li, G, Li, M, Yang, J, Liu, J. | 登録日 | 2019-04-14 | 公開日 | 2020-02-19 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Two distinct nucleic acid binding surfaces of Cdc5 regulate development. Biochem.J., 476, 2019
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2LEH
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![BU of 2leh by Molmil](/molmil-images/mine/2leh) | Solution structure of the core SMN-Gemin2 complex | 分子名称: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | 著者 | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | 登録日 | 2011-06-15 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445, 2012
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2LPT
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2MY3
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5LSO
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![BU of 5lso by Molmil](/molmil-images/mine/5lso) | |
2IFE
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7FP8
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![BU of 7fp8 by Molmil](/molmil-images/mine/7fp8) | PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P08H12 from the F2X-Universal Library | 分子名称: | A1 cistron-splicing factor AAR2, N~3~-[(2-bromophenyl)methyl]-N~3~-methyl-beta-alaninamide, Pre-mRNA-splicing factor 8 | 著者 | Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. | 登録日 | 2022-08-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022
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7FK3
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![BU of 7fk3 by Molmil](/molmil-images/mine/7fk3) | PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P04A09 from the F2X-Universal Library | 分子名称: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, methyl N-(benzenesulfonyl)-N-methylglycinate | 著者 | Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. | 登録日 | 2022-08-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022
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7FJW
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![BU of 7fjw by Molmil](/molmil-images/mine/7fjw) | PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P03H12 from the F2X-Universal Library | 分子名称: | 6-[(pyridin-2-yl)sulfanyl]pyridin-3-amine, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | 著者 | Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. | 登録日 | 2022-08-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022
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7FK1
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![BU of 7fk1 by Molmil](/molmil-images/mine/7fk1) | PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P04A06 from the F2X-Universal Library | 分子名称: | (3R)-3-(4-chlorobenzene-1-sulfonyl)butanoic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | 著者 | Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. | 登録日 | 2022-08-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022
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7FKO
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![BU of 7fko by Molmil](/molmil-images/mine/7fko) | PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P04E07 from the F2X-Universal Library | 分子名称: | 2-[(2-fluorophenyl)sulfanyl]acetohydrazide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | 著者 | Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. | 登録日 | 2022-08-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022
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