4PEH

Dbr1 in complex with synthetic linear RNA

Summary for 4PEH

• Entry DOI: 10.2210/pdb4peh/pdb
• Related: 4PEF 4PEG 4PEI
• Descriptor: RNA lariat debranching enzyme, putative, RNA (5'-R(*CP*UP*AP*(A2P)P*AP*CP*AP*A)-3'), MANGANESE (II) ION, ... (6 entities in total)
• Functional Keywords: nuclease, phosphodiesterase, metallohydrolase, metallophosphoesterase, lariat rna, hydrolase, metalloenzyme, hydrolase-rna complex, hydrolase/rna
• Biological source: Entamoeba histolytica; More
• Total number of polymer chains: 10
• Total formula weight: 218463.16

Authors

Montemayor, E.J.,Katolik, A.,Clark, N.E.,Taylor, A.B.,Schuermann, J.P.,Combs, D.J.,Johnsson, R.,Holloway, S.P.,Stevens, S.W.,Damha, M.J.,Hart, P.J. (deposition date: 2014-04-23, release date: 2014-08-27, Last modification date: 2023-12-27)

• Primary citation: Montemayor, E.J.,Katolik, A.,Clark, N.E.,Taylor, A.B.,Schuermann, J.P.,Combs, D.J.,Johnsson, R.,Holloway, S.P.,Stevens, S.W.,Damha, M.J.,Hart, P.J.; Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.; Nucleic Acids Res., 42:10845-10855, 2014; PubMed: 25123664; DOI: 10.1093/nar/gku725

Experimental method

X-RAY DIFFRACTION (2.1 Å)